Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 5/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | VDR | P11473 | 4/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.33 |
| ▸ | CNR2 | P34972 | 3/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.32 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.32 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6024086 | 1.00 | RXRA (0.39) | RXRARXRBRXRGPTGER4CYP4F2 | |
| SCHEMBL4079169 | 0.82 | KDM4E (0.44) | RXRARXRBRXRGPTGER4ALDH1A1 | |
| Potassium Ion SCHEMBL5819229 | 0.82 | KDM4E (0.43) | RXRARXRBRXRGPTGER4ALDH1A1 | |
| SCHEMBL5819232 | 0.82 | KDM4E (0.43) | RXRARXRBRXRGPTGER4ALDH1A1 | |
| SCHEMBL6023818 | 0.80 | MAPK1 (0.41) | MAPK1 | |
| SCHEMBL6023822 | 0.80 | MAPK1 (0.41) | MAPK1 | |
| SCHEMBL4089146 | 0.79 | CMKLR1 (0.37) | RXRARXRBRXRGALDH1A1HPGD | |
| SCHEMBL4094452 | 0.79 | CMKLR1 (0.37) | RXRARXRBRXRGCYP4F2CYP4A11 | |
| SCHEMBL4079746 | 0.77 | MCHR1 (0.37) | RXRARXRBRXRGPTGER4CYP4F2 | |
| SCHEMBL4079745 | 0.77 | MCHR1 (0.37) | RXRARXRBRXRGPTGER4CYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060004043-A1 | Indazole compounds and methods of use thereof | BHAGWAT SHRIPAD S | 2006-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060004043-A1 | Indazole compounds and methods of use thereof | WNT3, WNT3A, WNK3 | RXRA 2170/4885RXRB 2113/4885RXRG 2042/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.