SCHEMBL6025616

SCHEMBL6025616

CC(CCNC1(S(N)(=O)=O)C=CC=C([N+](=O)[O-])C1N(C(C)C)C(C)C)Sc1ccccc1

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
BCL2L1 Q07817 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6025289 0.93 BCL2L1 (0.32) BCL2L1
SCHEMBL6533302 0.82 BCL2L1 (0.31) BCL2L1
SCHEMBL6025033 0.74 MEN1 (0.31) BCL2L1
SCHEMBL6025521 0.62 KMT2A (0.42) BCL2L1
SCHEMBL6469780 0.62 BCL2L1 (0.34) BCL2L1
SCHEMBL6532201 0.62 POLB (0.42) BCL2L1
SCHEMBL6026291 0.59 KMT2A (0.41) BCL2L1
SCHEMBL6531288 0.59 MEN1 (0.40) BCL2L1
SCHEMBL6526602 0.58 CA2 (0.50)
SCHEMBL6470757 0.56 PKM (0.44)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1685119-A1 N-ACYLSULFONAMIDE APOPTOSIS PROMOTERS Abbott Laboratories (US) 2006-08-02 EP disclosed
WO-2005049594-A1 N-ACYLSULFONAMIDE APOPTOSIS PROMOTERS ABBOTT LABORATORIES (US) 2005-06-02 WO disclosed