Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7144290 | 0.74 | ALDH1A1 (0.57) | PKMKMT2ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL28150870 | 0.73 | SMN1; SMN2 (0.50) | PKMSMN1; SMN2ALDH1A1LMNABCAT1 | |
| SCHEMBL8484542 | 0.72 | PRMT1 (0.52) | PKMKMT2ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL8487122 | 0.70 | ALDH1A1 (0.47) | PKMKMT2ASMN1; SMN2ALDH1A1CYP2C9 | |
| SCHEMBL9234209 | 0.69 | ALDH1A1 (0.53) | PKMSMN1; SMN2ALDH1A1LMNABCAT1 | |
| SCHEMBL28197123 | 0.69 | BCAT1 (0.53) | PKMSMN1; SMN2ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL28360564 | 0.69 | ALDH1A1 (0.50) | KMT2ASMN1; SMN2ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL6526602 | 0.69 | CA2 (0.50) | — | |
| SCHEMBL22499521 | 0.68 | ALDH1A1 (0.56) | PKMSMN1; SMN2ALDH1A1LMNABCAT1 | |
| SCHEMBL3864255 | 0.67 | ALDH1A1 (0.57) | PKMKMT2ASMN1; SMN2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005049593-A2 | N-ACYLSULFONAMIDE APOPTOSIS PROMOTERS | ABBOTT LABORATORIES (US) | 2005-06-02 | — | — | WO | disclosed |