Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9924211 | 0.80 | DGAT1 (0.44) | DGAT1PDE10ADYRK1AAAK1 | |
| SCHEMBL19155694 | 0.74 | DGAT1 (0.37) | DGAT1AAK1 | |
| SCHEMBL5264614 | 0.73 | MKNK1 (0.49) | ALDH1A1KDM4EL3MBTL1DYRK1AMEN1 | |
| SCHEMBL19788662 | 0.72 | DGAT1 (0.35) | DGAT1AAK1 | |
| SCHEMBL1245617 | 0.72 | KMO (0.36) | KDM4EGAASMN1; SMN2HSD11B1 | |
| SCHEMBL11604848 | 0.72 | ALDH1A1 (0.42) | ALDH1A1KDM4EHPGDGAASMN1; SMN2 | |
| SCHEMBL28347818 | 0.71 | NOS3 (0.42) | ALDH1A1KDM4EHPGDGAAL3MBTL1 | |
| SCHEMBL10407781 | 0.70 | PDE10A (0.36) | DGAT1PDE10ADYRK1A | |
| SCHEMBL1245615 | 0.69 | CYP2C19 (0.34) | KCNN3KDR | |
| SCHEMBL20778316 | 0.68 | L3MBTL1 (0.35) | ALDH1A1KDM4EHPGDL3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119899187-A | Synthesis method of pyrazolo [1,5-a ] pyrimidine-7-amine compound | 湖南九典制药股份有限公司 | 2025-04-29 | — | — | CN | claimed |
| CN-119899187-A | Synthesis method of pyrazolo [1,5-a ] pyrimidine-7-amine compound | 湖南九典制药股份有限公司 | 2025-04-29 | — | — | CN | disclosed |
| CN-119899187-A | Synthesis method of pyrazolo [1,5-a ] pyrimidine-7-amine compound | 湖南九典制药股份有限公司 | 2025-04-29 | — | — | CN | disclosed |
| EP-1670801-A1 | PYRAZOLO AND IMIDAZO-PYRIMIDINE DERIVATIVES | F. Hoffmann-Roche AG (CH) | 2006-06-21 | — | — | EP | disclosed |
| WO-2005040171-A1 | PYRAZOLO AND IMIDAZO-PYRIMIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2005-05-06 | — | — | WO | disclosed |