SCHEMBL6026327

SCHEMBL6026327

C=Cc1ccc(COCC2CCCO2)cc1

nearest known ligand 0.41

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.38
DRD2 P14416 1/20 0.38
HTR2A P28223 1/20 0.38
HRH1 P35367 1/20 0.38
PRMT5 O14744 1/20 0.37
WDR77 Q9BQA1 1/20 0.37
MGLL Q99685 2/20 0.37
KMT2A Q03164 1/20 0.36
MAPT P10636 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7925280 0.84 ATM (0.38) DRD2HTR2AHRH1PRMT5WDR77
SCHEMBL16019154 0.83 LMNA (0.32)
SCHEMBL239227 0.83 ALDH1A1 (0.46) MGLL
SCHEMBL14777169 0.81 ALDH1A1 (0.38) MAPT
SCHEMBL6151122 0.81 ALDH1A1 (0.38) MAPT
SCHEMBL21283683 0.80 LMNA (0.50)
SCHEMBL5660476 0.80 LMNA (0.50)
SCHEMBL16273365 0.79 LMNA (0.42) HPGD
SCHEMBL12260675 0.77 MGLL (0.41) HPGDPRMT5WDR77MGLL
SCHEMBL1269546 0.77 ALDH1A1 (0.42) MGLLKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1177182-B1 NOVEL PHOTOINITIATORS AND THEIR APPLICATIONS CIBA SC HOLDING AG (CH) 2006-11-29 EP disclosed
EP-1086145-B1 PHOTOINITIATORS AND THEIR APPLICATIONS CIBA SC HOLDING AG (CH) 2004-05-12 EP disclosed
US-6673850-B1 ODORLESS PHOTOINITIATOR COMPOUNDS HAVING CHAIN TRANSFER GROUPS CIBA SPECIALTY CHEMICALS CORPORATION 2004-01-06 US disclosed
US-6489081-B1 Organosilyl radical generators and their applications CIBA SPECIALTY CHEMICALS CORPORATION 2002-12-03 US disclosed
US-6458864-B1 CHAIN TRANSFER GROUPS OF THE FORMULA ARE SUITABLE FOR THE THERMAL PREPARATION OF MACROPHOTOINITIATORS WHICH ARE POLYMERIZED PHOTOCHEMICALLY TO GIVE BLOCK-COPOLYMERS. CIBA SPECIALTY CHEMICALS CORPORATION 2002-10-01 US disclosed
EP-1108723-B1 Organosilyl radical generators and their applications CIBA SC HOLDING AG (CH) 2002-09-18 EP disclosed
EP-1177182-A1 NOVEL PHOTOINITIATORS AND THEIR APPLICATIONS Ciba SC Holding AG (CH) 2002-02-06 EP disclosed
EP-1108723-A1 Organosilyl radical generators and their applications Ciba SC Holding AG (CH) 2001-06-20 EP disclosed
EP-1086145-A1 NOVEL PHOTOINITIATORS AND THEIR APPLICATIONS Ciba SC Holding AG (CH) 2001-03-28 EP disclosed
WO-2000068218-A1 NOVEL PHOTOINITIATORS AND THEIR APPLICATIONS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2000-11-16 WO disclosed
WO-1999062961-A1 NOVEL PHOTOINITIATORS AND THEIR APPLICATIONS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1999-12-09 WO disclosed