Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL242446 | 0.85 | ALDH1A1 (0.41) | LMNAALDH1A1 | |
| SCHEMBL31290756 | 0.85 | ALDH1A1 (0.41) | LMNAALDH1A1 | |
| SCHEMBL6026327 | 0.84 | HPGD (0.38) | DRD2HTR2AHRH1PRMT5WDR77 | |
| SCHEMBL21283683 | 0.79 | LMNA (0.50) | LMNA | |
| SCHEMBL5660476 | 0.79 | LMNA (0.50) | LMNA | |
| SCHEMBL6574231 | 0.75 | TP53 (0.47) | ALDH1A1 | |
| SCHEMBL16138311 | 0.75 | MGLL (0.49) | LMNA | |
| SCHEMBL16138331 | 0.75 | MGLL (0.49) | LMNA | |
| SCHEMBL16138316 | 0.75 | MGLL (0.49) | LMNA | |
| SCHEMBL1357316 | 0.72 | ALDH1A1 (0.40) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6231783-B1 | SOLVENT SYSTEMS HAVING IMPROVED PHYSICAL PROPERTIES TO MINIMIZE ENTRY INTO THE ENVIRONMENT AND TO FACILITATE SEPARATIONS AND CLEANING OPERATIONS TO MINIMIZE POLLUTION | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2001-05-15 | — | — | US | disclosed |
| WO-1997018179-A1 | REPLACEMENT SOLVENTS FOR USE IN CHEMICAL SYNTHESIS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1997-05-22 | — | — | WO | disclosed |