Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 6/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6887943 | 0.90 | RAB9A (0.38) | BRD4RAB9ANPC1MAPTMEN1 | |
| SCHEMBL6027185 | 0.88 | PTPN1 (0.44) | BRD4RAB9ANPC1MAPTKMT2A | |
| SCHEMBL6026610 | 0.87 | BRD4 (0.44) | BRD4RAB9ANPC1MAPTMEN1 | |
| SCHEMBL6026685 | 0.81 | PTPN1 (0.44) | BRD4RAB9ANPC1MAPTKMT2A | |
| SCHEMBL6887912 | 0.80 | NPSR1 (0.45) | BRD4RAB9ANPC1MEN1KMT2A | |
| SCHEMBL6027333 | 0.80 | BRD4 (0.42) | BRD4RAB9ANPC1MAPTMEN1 | |
| SCHEMBL6888532 | 0.77 | MAPT (0.37) | BRD4RAB9ANPC1MAPTMEN1 | |
| SCHEMBL6885880 | 0.76 | SCN3A (0.42) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL6027147 | 0.76 | SCN3A (0.39) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL6030700 | 0.76 | PTPN1 (0.51) | RAB9ANPC1HPGDSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1613310-A1 | IMIDAZOLE DERIVATIVES FOR TREATMENT OF ALLERGIC AND HYPERPROLIFERATIVE DISORDERS | Avanir Pharmaceuticals (US) | 2006-01-11 | — | — | EP | disclosed |
| WO-2004091610-A1 | IMIDAZOLE DERIVATIVES FOR TREATMENT OF ALLERGIC AND HYPERPROLIFERATIVE DISORDERS | AVANIR PHARMACEUTICALS (US) | 2004-10-28 | — | — | WO | disclosed |