SCHEMBL9575640

SCHEMBL9575640

CCO[Si](CCCOc1ccc(CC(C)(O)C=O)cc1)(OCC)OCC

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.39
ALDH1A1 P00352 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
MAPT P10636 1/20 0.39
HPGD P15428 1/20 0.39
PPARD Q03181 2/20 0.37
PPARA Q07869 2/20 0.37
POLB P06746 1/20 0.36
ACACB O00763 1/20 0.36
PPARG P37231 1/20 0.36
EBP Q15125 1/20 0.36
SIGMAR1 Q99720 1/20 0.36
EPHX2 P34913 1/20 0.36
NR1H4 Q96RI1 1/20 0.36
LTA4H P09960 3/20 0.36
FAAH O00519 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9575778 0.94 LMNA (0.37) LMNAALDH1A1SMN1; SMN2MAPTHPGD
SCHEMBL6027401 0.80 NR5A1 (0.51)
SCHEMBL788296 0.78 SMN1; SMN2 (0.50) LMNAALDH1A1SMN1; SMN2MAPTHPGD
SCHEMBL19644362 0.78 SMN1; SMN2 (0.50) LMNAALDH1A1SMN1; SMN2MAPTHPGD
SCHEMBL9614864 0.77 SMN1; SMN2 (0.48) LMNAALDH1A1SMN1; SMN2MAPTHPGD
SCHEMBL8673385 0.75 POLB (0.44) LMNASMN1; SMN2PPARAPOLB
SCHEMBL10455828 0.75 LMNA (0.39) LMNAALDH1A1SMN1; SMN2MAPTHPGD
SCHEMBL20226244 0.74 SMN1; SMN2 (0.44) LMNAALDH1A1SMN1; SMN2MAPTHPGD
SCHEMBL3975354 0.74 THRA (0.38) LMNAALDH1A1SMN1; SMN2MAPTHPGD
SCHEMBL4738118 0.74 LTA4H (0.46) LMNAALDH1A1SMN1; SMN2HPGDPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0281941-B1 Coreactive photoinitiators CIBA GEIGY AG (CH) 1993-12-08 EP claimed