Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRC | Q99895 | 3/20 | 0.43 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.42 |
| ▸ | KMO | O15229 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | VCP | P55072 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2840069 | 0.80 | KMO (0.54) | CTRCADORA3KMOKMT2ACYP3A4 | |
| SCHEMBL6027661 | 0.72 | SMN1; SMN2 (0.60) | MAPTTP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL2839700 | 0.69 | KDM4E (0.48) | CTRCCXCL12ADORA3KMOKMT2A | |
| SCHEMBL17826985 | 0.69 | CXCL12 (0.49) | CTRCCXCL12ADORA3KMT2AMAPT | |
| SCHEMBL2614936 | 0.68 | CXCL12 (0.54) | CXCL12ADORA3KMOKMT2AMAPT | |
| SCHEMBL3646180 | 0.68 | CYP3A4 (0.65) | KMT2ATP53CYP3A4ALDH1A1 | |
| SCHEMBL18604297 | 0.68 | MAPT (0.54) | MAPTTP53CYP3A4ALDH1A1 | |
| SCHEMBL2836839 | 0.68 | CTRC (0.45) | CTRCCXCL12ADORA3KMOKMT2A | |
| SCHEMBL2841068 | 0.67 | CTRC (0.44) | CTRCCXCL12ADORA3KMOKMT2A | |
| SCHEMBL13066924 | 0.67 | KMO (0.52) | CTRCCXCL12ADORA3KMOKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720829-A1 | DERIVATIVES OF HETEROARYL-ALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | Sanofi-Aventis (FR) | 2006-11-15 | — | — | EP | disclosed |
| WO-2005090292-A1 | DERIVATIVES OF HETEROARYL-ALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | SANOFI-AVENTIS (FR) | 2005-09-29 | — | — | WO | disclosed |