Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | PARP1 | P09874 | 9/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | DAO | P14920 | 1/20 | 0.47 |
| ▸ | PARP2 | Q9UGN5 | 3/20 | 0.46 |
| ▸ | B3GNT2 | Q9NY97 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30704833 | 1.00 | SMN1; SMN2 (0.53) | SMN1; SMN2TSHRHSD17B10TDP1L3MBTL1 | |
| SCHEMBL17242599 | 0.88 | PARP1 (0.49) | ALDH1A1PARP1KDM4EDAOPARP2 | |
| SCHEMBL6300121 | 0.88 | PARP1 (0.46) | SMN1; SMN2TSHRHSD17B10TDP1L3MBTL1 | |
| SCHEMBL6027805 | 0.81 | CYP1A2 (0.64) | ALDH1A1PARP1KDM4EHPGDDAO | |
| SCHEMBL6800624 | 0.80 | DAO (0.43) | PARP1DAOCYP1A2CYP2C19 | |
| SCHEMBL2267066 | 0.80 | CYP1A2 (0.67) | SMN1; SMN2TSHRHSD17B10TDP1L3MBTL1 | |
| SCHEMBL6295245 | 0.79 | PARP1 (0.53) | ALDH1A1PARP1DAOPARP2CYP1A2 | |
| SCHEMBL14160795 | 0.78 | ALDH1A1 (0.63) | SMN1; SMN2TSHRHSD17B10TDP1L3MBTL1 | |
| SCHEMBL2800361 | 0.77 | BACE1 (0.63) | SMN1; SMN2TSHRHSD17B10TDP1L3MBTL1 | |
| SCHEMBL29643235 | 0.77 | BACE1 (0.63) | SMN1; SMN2TSHRHSD17B10TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230203003-A1 | Notch Inhibitors and Uses Thereof | STEMSYNERGY THERAPEUTICS, INC. | 2023-06-29 | — | — | US | disclosed |
| US-8501786-B2 | Hydroxymethyl pyrrolidines as beta 3 adrenergic receptor agonists | MERCK SHARP & DOHME CORP. (US) | 2013-08-06 | — | — | US | disclosed |
| US-20110028461-A1 | HYDROXYMETHYL PYRROLIDINES AS BETA 3 ADRENERGIC RECEPTOR AGONISTS | MERCK SHARP & DOHME LLC | 2011-02-03 | — | — | US | disclosed |
| US-7018786-B2 | Toning agents for use in thermographic recording materials | AGFA GEVAERT (BE) | 2006-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230203003-A1 | Notch Inhibitors and Uses Thereof | NOTCH1, NOTCH2, NOTCH4 | SMN1; SMN2 4659/4885TSHR 3942/4885HSD17B10 2619/4885 |
| US-20110028461-A1 | HYDROXYMETHYL PYRROLIDINES AS BETA 3 ADRENERGIC RECEPTOR AGONISTS | ADRB3, ADRB1, ADRB2 | SMN1; SMN2 3396/4885TSHR 346/4885HSD17B10 1355/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.