Sugi Predict

Sugi Predict / Compounds / SCHEMBL6028396

SCHEMBL6028396

SCHEMBL6028396

O=C(CCl)ONc1ccc(-c2ccccc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 3/20 0.57
▸ HTT P42858 2/20 0.57
▸ NPC1 O15118 1/20 0.57
▸ MITF O75030 1/20 0.57
▸ RAB9A P51151 1/20 0.57
▸ SMN1; SMN2 Q16637 1/20 0.57
▸ PTPN1 P18031 2/20 0.44
▸ PTPN11 Q06124 1/20 0.44
▸ SLC1A3 P43003 1/20 0.43
▸ SLC1A2 P43004 1/20 0.43
▸ SLC1A1 P43005 1/20 0.43
▸ TAAR1 Q96RJ0 1/20 0.42
▸ RNF4 P78317 1/20 0.41
▸ CNR1 P21554 1/20 0.41
▸ CASR P41180 1/20 0.41
▸ KMT2A Q03164 2/20 0.41
▸ FFAR1 O14842 2/20 0.41
▸ PKM P14618 1/20 0.41
▸ CASP3 P42574 1/20 0.41
▸ SENP7 Q9BQF6 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10648021 0.80 GSK3B (0.44) ALDH1A1NPC1RAB9ASMN1; SMN2CNR1
SCHEMBL11685657 0.75 KMT2A (0.44) ALDH1A1SMN1; SMN2KMT2APKMCASP3
Biphenyl SCHEMBL10773823 0.75 ALDH1A1 (0.50) ALDH1A1HTTNPC1MITFRAB9A
SCHEMBL27439138 0.74 KMT2A (0.43) ALDH1A1HTTRAB9ASMN1; SMN2KMT2A
SCHEMBL13842150 0.73 PTPN1 (0.47) ALDH1A1HTTNPC1MITFRAB9A
SCHEMBL2330263 0.73 ALDH1A1 (1.00) ALDH1A1HTTNPC1MITFRAB9A
SCHEMBL7058052 0.72 HDAC1 (0.49) ALDH1A1HTTNPC1MITFRAB9A
SCHEMBL27607230 0.71 GAA (0.49) ALDH1A1HTTRAB9ASMN1; SMN2KMT2A
Biphenyl SCHEMBL8675329 0.70 ALDH1A1 (0.57) ALDH1A1HTTNPC1MITFRAB9A
SCHEMBL7913267 0.69 MAPT (0.47) ALDH1A1NPC1RAB9ASMN1; SMN2TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6986886-B2 Hair conditioning compositions and their use in hair coloring compositions THE PROCTER & GAMBLE COMPANY (US) 2006-01-17 — — US disclosed
US-20040158941-A1 Hair colouring and conditioning compositions THE PROCTER & GAMBLE COMPANY (US) 2004-08-19 — — US disclosed
US-20040158938-A1 Method for colouring hair THE PROCTER & GAMBLE COMPANY 2004-08-19 — — US disclosed
CN-1153562-C Hair coloring compositions ���޿��غ͸ʱ�����˾ 2004-06-16 — — CN disclosed
US-6695888-B2 COMPLEX TRANSITION METAL HAIR DYE UNILEVER HOME & PERSONAL CARE, USA, DIVISION OF CONOPCO, INC. 2004-02-24 — — US disclosed
WO-2004014328-A1 ONE STEP HAIR COLORING COMPOSITIONS COMPRISING WATER SOLUBLE CARBONATE RELEASING SALTS UNILEVER PLC (GB) 2004-02-19 — — WO disclosed
US-20040019980-A1 One step hair coloring compositions using salts UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2004-02-05 — — US disclosed
US-20030219399-A1 Hair conditioning compositions and their use in hair colouring compositions THE PROCTER & GAMBLE COMPANY (US) 2003-11-27 — — US disclosed
EP-1341502-A2 HAIR CONDITIONING COMPOSITIONS AND THEIR USE IN HAIR COLOURING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2003-09-10 — — EP disclosed
EP-0876134-B1 HAIR COLORING COMPOSITIONS PROCTER & GAMBLE (US) 2003-09-03 — — EP disclosed
EP-0869769-A1 HAIR BLEACHING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1998-10-14 — — EP disclosed
WO-1998027943-A1 HAIR COLORING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1998-07-02 — — WO disclosed
WO-1998027945-A1 HAIR COLORING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1998-07-02 — — WO disclosed
WO-1998027944-A1 HAIR COLORING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1998-07-02 — — WO disclosed
WO-1998027942-A1 HAIR COLORING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1998-07-02 — — WO disclosed
WO-1998027941-A1 HAIR COLORING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1998-07-02 — — WO disclosed
WO-1997024107-A1 HAIR COLORING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1997-07-10 — — WO disclosed
WO-1997024105-A1 HAIR COLORING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1997-07-10 — — WO disclosed
WO-1997024106-A1 HAIR COLORING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1997-07-10 — — WO disclosed
WO-1997024108-A1 HAIR BLEACHING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1997-07-10 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030219399-A1 Hair conditioning compositions and their use in hair colouring compositions CD99, HLA-C, PLOD1 ALDH1A1 1318/4885HTT 893/4885NPC1 4885/4885
US-20040158941-A1 Hair colouring and conditioning compositions FNIP1, CUTA, SHH ALDH1A1 1162/4885HTT 272/4885NPC1 4844/4885
US-20040158938-A1 Method for colouring hair COX5B, SHH, DNMT3A ALDH1A1 209/4885HTT 766/4885NPC1 4606/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.