Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.54 |
| ▸ | ITGAV | P06756 | 6/20 | 0.54 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.54 |
| ▸ | MMP7 | P09237 | 1/20 | 0.52 |
| ▸ | MMP1 | P03956 | 2/20 | 0.50 |
| ▸ | MMP2 | P08253 | 2/20 | 0.50 |
| ▸ | MMP9 | P14780 | 2/20 | 0.50 |
| ▸ | MMP8 | P22894 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.49 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.48 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7754801 | 0.78 | BACE1 (0.66) | ITGB3ITGAVITGA2BMMP7MMP1 | |
| SCHEMBL3924110 | 0.78 | BACE1 (0.66) | ITGB3ITGAVITGA2BMMP7MMP1 | |
| SCHEMBL7375788 | 0.76 | SLC1A3 (0.66) | ITGB3ITGAVITGA2BMMP7MMP1 | |
| Trifluoroacetic Acid SCHEMBL7656969 | 0.75 | SLC1A3 (0.62) | ITGB3ITGAVITGA2BMMP7MMP1 | |
| SCHEMBL6896602 | 0.72 | BACE1 (0.59) | ITGAVMMP2MMP9CTSLCTSS | |
| SCHEMBL7656972 | 0.72 | MMP7 (0.55) | ITGB3ITGAVITGA2BMMP7MMP1 | |
| SCHEMBL5191038 | 0.72 | L3MBTL1 (0.80) | MMP7MMP1MMP2MMP9MMP13 | |
| SCHEMBL7065939 | 0.71 | NPSR1 (0.68) | ITGB3ITGAVITGA2BMMP7MMP1 | |
| SCHEMBL4145606 | 0.71 | EEF2K (0.76) | ITGB3ITGAVMMP7MMP1MMP2 | |
| SCHEMBL27568136 | 0.71 | POLB (0.70) | MMP7MMP1MMP2MMP9CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633354-A2 | N-(((((1,3-THIAZOL-2-YL)AMINO)CARBONYL)PHENYL)SULFONYL)PHENYLALANINE DERIVATIVES AND RELATED COMPOUNDS FOR THE TREATMENT OF DIABETES | The Institutes for Pharmaceutical Discovery, LLC (US) | 2006-03-15 | — | — | EP | claimed |
| WO-2004092146-A2 | N- (((((1,3-THIAZOL-2-YL) AMINO) CARBONYL) PHENYL) SULFONYL) PHENYLALANINE DERIVATIVES AND RELATED COMPOUNDS FOR THE TREATMENT OF DIABETES | THE INSTITUTES FOR PHARMACEUTICAL DISCOVERY, LLC (US) | 2004-10-28 | — | — | WO | claimed |