Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.74 |
| ▸ | TSHR | P16473 | 1/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.74 |
| ▸ | APP | P05067 | 2/20 | 0.57 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.50 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19987394 | 0.87 | CYP3A4 (0.56) | CYP3A4ALDH1A1TSHRTDP1APP | |
| 4,4'-Methylenedianiline SCHEMBL15105282 | 0.86 | CYP3A4 (1.00) | CYP3A4ALDH1A1TSHRTDP1GFER | |
| 4,4'-Methylenedianiline SCHEMBL28001 | 0.86 | CYP3A4 (1.00) | CYP3A4ALDH1A1TSHRTDP1GFER | |
| SCHEMBL1304762 | 0.86 | CYP3A4 (1.00) | CYP3A4ALDH1A1TSHRTDP1GFER | |
| SCHEMBL6362775 | 0.86 | CYP3A4 (1.00) | CYP3A4ALDH1A1TSHRTDP1GFER | |
| SCHEMBL8094139 | 0.86 | CYP3A4 (1.00) | CYP3A4ALDH1A1TSHRTDP1GFER | |
| SCHEMBL5491719 | 0.86 | CYP3A4 (0.50) | CYP3A4ALDH1A1TSHRTDP1APP | |
| SCHEMBL3482770 | 0.86 | CYP3A4 (1.00) | CYP3A4ALDH1A1TSHRTDP1GFER | |
| 4,4'-Methylenedianiline SCHEMBL2529236 | 0.83 | CYP3A4 (0.93) | CYP3A4ALDH1A1TSHRTDP1GFER | |
| 4,4'-Methylenedianiline SCHEMBL5712040 | 0.83 | CYP3A4 (0.93) | CYP3A4ALDH1A1TSHRTDP1GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080064662-A1 | Methods and compositions for modulating sphingosine -1- phosphate (S1P) receptor activity | PRAECIS PHARMACEUTICALS INCORPORATED (US) | 2008-03-13 | — | — | US | disclosed |
| US-7241812-B2 | Methods and compositions for modulating sphingosine-1-phosphate (S1P) receptor activity | PRAECIS PHARMACEUTICALS, INC. (US) | 2007-07-10 | — | — | US | disclosed |
| US-6986886-B2 | Hair conditioning compositions and their use in hair coloring compositions | THE PROCTER & GAMBLE COMPANY (US) | 2006-01-17 | — | — | US | disclosed |
| US-20040158941-A1 | Hair colouring and conditioning compositions | THE PROCTER & GAMBLE COMPANY (US) | 2004-08-19 | — | — | US | disclosed |
| US-20040158938-A1 | Method for colouring hair | THE PROCTER & GAMBLE COMPANY | 2004-08-19 | — | — | US | disclosed |
| US-6695888-B2 | COMPLEX TRANSITION METAL HAIR DYE | UNILEVER HOME & PERSONAL CARE, USA, DIVISION OF CONOPCO, INC. | 2004-02-24 | — | — | US | disclosed |
| US-20040019980-A1 | One step hair coloring compositions using salts | UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. | 2004-02-05 | — | — | US | disclosed |
| US-20030219399-A1 | Hair conditioning compositions and their use in hair colouring compositions | THE PROCTER & GAMBLE COMPANY (US) | 2003-11-27 | — | — | US | disclosed |
| EP-0876134-B1 | HAIR COLORING COMPOSITIONS | PROCTER & GAMBLE (US) | 2003-09-03 | — | — | EP | disclosed |
| US-20030110579-A1 | Method for colouring hair | THE PROCTER & GAMBLE COMPANY (US) | 2003-06-19 | — | — | US | disclosed |
| EP-0869769-A1 | HAIR BLEACHING COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1998-10-14 | — | — | EP | disclosed |
| WO-1998027943-A1 | HAIR COLORING COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1998-07-02 | — | — | WO | disclosed |
| WO-1998027945-A1 | HAIR COLORING COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1998-07-02 | — | — | WO | disclosed |
| WO-1998027942-A1 | HAIR COLORING COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1998-07-02 | — | — | WO | disclosed |
| WO-1998027944-A1 | HAIR COLORING COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1998-07-02 | — | — | WO | disclosed |
| WO-1998027941-A1 | HAIR COLORING COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1998-07-02 | — | — | WO | disclosed |
| WO-1997024108-A1 | HAIR BLEACHING COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1997-07-10 | — | — | WO | disclosed |
| WO-1997024106-A1 | HAIR COLORING COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1997-07-10 | — | — | WO | disclosed |
| WO-1997024105-A1 | HAIR COLORING COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1997-07-10 | — | — | WO | disclosed |
| WO-1997024107-A1 | HAIR COLORING COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1997-07-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080064662-A1 | Methods and compositions for modulating sphingosine -1- phosphate (S1P) receptor activity | S1PR1, S1PR2, S1PR3 | CYP3A4 4654/4885ALDH1A1 3708/4885TSHR 642/4885 |
| US-20030110579-A1 | Method for colouring hair | COX5B, SHH, DNMT3A | CYP3A4 1944/4885ALDH1A1 209/4885TSHR 3767/4885 |
| US-20030219399-A1 | Hair conditioning compositions and their use in hair colouring compositions | CD99, HLA-C, PLOD1 | CYP3A4 4370/4885ALDH1A1 1318/4885TSHR 4180/4885 |
| US-20040158941-A1 | Hair colouring and conditioning compositions | FNIP1, CUTA, SHH | CYP3A4 4246/4885ALDH1A1 1162/4885TSHR 2357/4885 |
| US-20040158938-A1 | Method for colouring hair | COX5B, SHH, DNMT3A | CYP3A4 1944/4885ALDH1A1 209/4885TSHR 3767/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.