SCHEMBL6029429

SCHEMBL6029429

Nc1ccc(O)c(Cc2ccccc2)c1

nearest known ligand 0.62

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.62
CYP3A4 P08684 1/20 0.62
HPGD P15428 1/20 0.62
ALOX15 P16050 1/20 0.62
KMT2A Q03164 1/20 0.62
HIF1A Q16665 1/20 0.62
HSD17B10 Q99714 1/20 0.62
BCL2 P10415 1/20 0.59
BCL2L1 Q07817 1/20 0.59
SLC7A5 Q01650 1/20 0.54
ALOX5 P09917 1/20 0.52
IDH1 O75874 1/20 0.50
PRKCI P41743 1/20 0.50
ACHE P22303 3/20 0.49
HTR2A P28223 1/20 0.46
KEAP1 Q14145 1/20 0.46
HSP90AA1 P07900 2/20 0.45
HNF4A P41235 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL10882487 0.98 MEN1 (0.61) MEN1CYP3A4HPGDALOX15KMT2A
Propionic Acid SCHEMBL27458535 0.89 SLC7A5 (0.52) MEN1CYP3A4HPGDALOX15KMT2A
SCHEMBL21010899 0.85 KEAP1 (0.55) MEN1CYP3A4HPGDALOX15KMT2A
SCHEMBL30597925 0.83 PRKCI (0.61) MEN1CYP3A4HPGDALOX15KMT2A
SCHEMBL29358019 0.83 PRKCI (0.61) MEN1CYP3A4HPGDALOX15KMT2A
SCHEMBL111004 0.83 PRKCI (0.61) MEN1CYP3A4HPGDALOX15KMT2A
SCHEMBL11794729 0.81 ALOX15 (0.59) MEN1CYP3A4HPGDALOX15KMT2A
SCHEMBL15993786 0.81 PRKCI (0.59) MEN1CYP3A4HPGDALOX15KMT2A
Hydrochloric Acid SCHEMBL22612460 0.81 ACHE (0.62) MEN1CYP3A4HPGDALOX15KMT2A
Hydrochloric Acid SCHEMBL3337180 0.81 ACHE (0.62) MEN1CYP3A4HPGDALOX15KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022191865-A1 HAIR COLORANT ASSESSMENT, SELECTION AND FORMULATION SYSTEM Innovative Beauty LLC (US) 2022-09-15 WO disclosed
US-20220283032-A1 Hair Colorant Assessment, Selection And Formulation System Innovative Beauty LLC (US) 2022-09-08 US disclosed
US-11378457-B1 Hair colorant assessment, selection and formulation system Innovative Beauty LLC (US) 2022-07-05 US disclosed
US-11137291-B1 Hair colorant assessment, selection and formulation system Innovative Beauty LLC (US) 2021-10-05 US disclosed
CN-102301442-A Flat-panel display member, and paste for the uppermost layer of partition wall of flat-panel display member 2011-12-28 CN disclosed
CN-100366233-C Hair conditioning compositions and application in hair dye composition thereof PROCTER & GAMBLE (US) 2008-02-06 CN disclosed
US-6986886-B2 Hair conditioning compositions and their use in hair coloring compositions THE PROCTER & GAMBLE COMPANY (US) 2006-01-17 US disclosed
CN-1209094-C Hair coloring compositions and methods PROCTER & GAMBLE (US) 2005-07-06 CN disclosed
US-20040158941-A1 Hair colouring and conditioning compositions THE PROCTER & GAMBLE COMPANY (US) 2004-08-19 US disclosed
US-20040158938-A1 Method for colouring hair THE PROCTER & GAMBLE COMPANY 2004-08-19 US disclosed
US-4159245-A PASSING THROUGH DIAPHRAGM COMPRISING POLYTETRAFLUOROETHYLENE, OR A MIXTURE WITH POLYPROPYLENE, POLYETHYLENE OR POLYVINYL CHLORIDE FUJI PHOTO FILM CO., LTD. (JP) 1979-06-26 US disclosed
US-4147546-A COBALT III COMPLEX, COLOR INTENSIFICATION, POLYTETRAFLUOROETHYLENE PERMSELECTIVE MEMBRANE FUJI PHOTO FILM CO., LTD. (JP) 1979-04-03 US disclosed
US-4146397-A Method of forming a photographic image FUJI PHOTO FILM CO., LTD. (JP) 1979-03-27 US disclosed
US-4069050-A INTENSIFICATION WITH FOG CONTROL FUJI PHOTO FILM CO., LTD. (JA) 1978-01-17 US disclosed
US-4062684-A ANTIFOGGING, NITROGEN HETEROCYCLE FUJI PHOTO FILM CO., LTD. (JA) 1977-12-13 US disclosed
US-4045226-A AN ANTIFOGGING VINYL AMIDE COPOLYMER AND PEROXIDE INTENSIFIER FUJI PHOTO FILM CO., LTD. (JA) 1977-08-30 US disclosed
US-4045225-A AN ANTIFOGGING NITRO-SUBSTITUTED ISOINDAZOLE, BENZIMIDAZOLE OR BENZOTRIAZOLE, AND HYDROGEN PEROXIDE OR HALOGENITE OXIDIZER FUJI PHOTO FILM CO., LTD. (JA) 1977-08-30 US disclosed
US-4043814-A CONTACTING PHOTOGRAPHIC ELEMENT WITH A CHLORITE OR BROMITE, CHLOROUS OR BROMOUS ACID, OR CHLORINE DIOXIDE FUJI PHOTO FILM CO., LTD. (JA) 1977-08-23 US disclosed
US-4004927-A Photographic light-sensitive material containing liquid organopolysiloxane FUJI PHOTO FILM CO., LTD. (JA) 1977-01-25 US disclosed
US-3957424-A Enzyme-activated oxidative process for coloring hair THE PROCTER & GAMBLE COMPANY (US) 1976-05-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040158941-A1 Hair colouring and conditioning compositions FNIP1, CUTA, SHH MEN1 953/4885CYP3A4 4246/4885HPGD 2400/4885
US-20040158938-A1 Method for colouring hair COX5B, SHH, DNMT3A MEN1 2883/4885CYP3A4 1944/4885HPGD 2102/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.