Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | GNAI3 | P08754 | 4/20 | 0.35 |
| ▸ | GNAO1 | P09471 | 4/20 | 0.35 |
| ▸ | GNAI1 | P63096 | 4/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 2/20 | 0.31 |
| ▸ | PLAUR | Q03405 | 2/20 | 0.31 |
| ▸ | EP300 | Q09472 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | RAD52 | P43351 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10413132 | 0.93 | SIGMAR1 (0.43) | SIGMAR1GNAI3GNAO1GNAI1OPRD1 | |
| SCHEMBL4559648 | 0.83 | SIGMAR1 (0.43) | SIGMAR1OPRD1PLAUPLAURSLC6A4 | |
| SCHEMBL1077282 | 0.83 | SIGMAR1 (0.38) | SIGMAR1OPRD1SLC6A4 | |
| SCHEMBL1900357 | 0.82 | SIGMAR1 (0.58) | SIGMAR1GNAI3GNAO1GNAI1OPRD1 | |
| SCHEMBL2764645 | 0.80 | SIGMAR1 (0.38) | SIGMAR1OPRD1PLAUPLAURSLC6A4 | |
| SCHEMBL1905214 | 0.78 | SIGMAR1 (0.47) | SIGMAR1SLC6A4 | |
| SCHEMBL8488533 | 0.78 | PLAU (0.36) | SIGMAR1OPRD1PLAUPLAURSLC6A4 | |
| SCHEMBL29085077 | 0.77 | SIGMAR1 (0.41) | SIGMAR1 | |
| SCHEMBL6152515 | 0.76 | L3MBTL1 (0.46) | SIGMAR1SLC6A4L3MBTL1 | |
| SCHEMBL4557394 | 0.74 | MEN1 (0.39) | SIGMAR1OPRD1MEN1KMT2ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060020064-A1 | Flame-retardant polymer molding compositions | CLARIANT GMBH | 2006-01-26 | — | — | US | disclosed |
| WO-1999010276-A1 | SILICATE-CONTAINING COMPOSITE MATERIAL | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-03-04 | — | — | WO | disclosed |
| US-4130517-A | Multiphase block and graft copolymers comprising a hydrophilic continuous phase and hydrophobic domains | EXXON RESEARCH & ENGINEERING CO. (US) | 1978-12-19 | — | — | US | disclosed |
| US-4104824-A | WATER RETENTION AGENTS FOR AGRICULTURAL USE | EXXON RESEARCH & ENGINEERING CO. (US) | 1978-08-08 | — | — | US | disclosed |
| US-4057598-A | Multiphase block and graft copolymers comprising a hydrophilic continuous phase and hydrophobic domains | EXXON RESEARCH & ENGINEERING CO. (US) | 1977-11-08 | — | — | US | disclosed |