Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.48 |
| ▸ | RARB | P10826 | 12/20 | 0.40 |
| ▸ | RARG | P13631 | 11/20 | 0.40 |
| ▸ | RARA | P10276 | 10/20 | 0.40 |
| ▸ | RXRA | P19793 | 9/20 | 0.39 |
| ▸ | RXRB | P28702 | 6/20 | 0.39 |
| ▸ | RXRG | P48443 | 5/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GCK | P35557 | 1/20 | 0.36 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6032634 | 0.83 | RXRA (0.43) | CYP3A4CYP26A1RARBRARGRARA | |
| SCHEMBL6033244 | 0.79 | RARB (0.39) | CYP3A4CYP26A1RARBRARGRARA | |
| SCHEMBL6882380 | 0.74 | RARB (0.46) | CYP3A4CYP26A1RARBRARGRARA | |
| SCHEMBL6033044 | 0.74 | RXRA (0.59) | CYP26A1RARBRARGRARARXRA | |
| SCHEMBL4956919 | 0.74 | RXRA (0.51) | CYP3A4CYP26A1RARBRARGRARA | |
| SCHEMBL7471196 | 0.72 | CYP3A4 (0.56) | CYP3A4CYP26A1RARBRARGRARA | |
| SCHEMBL6032638 | 0.70 | RARA (0.30) | RARBRARGRARA | |
| SCHEMBL6033347 | 0.70 | RXRA (0.56) | CYP3A4CYP26A1RARBRARGRARA | |
| SCHEMBL6032956 | 0.69 | RXRA (0.46) | CYP3A4CYP26A1RARBRARGRARA | |
| SCHEMBL6033277 | 0.69 | HCAR3 (0.34) | RARBRARGRARARXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060014803-A1 | Diarylselenide compounds and their use in human or veterinary medicine and in cosmetics | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2006-01-19 | — | — | US | claimed |
| EP-1086080-B1 | DIARYLSELENIDE COMPOUNDS AND THEIR USE IN HUMAN OR VETERINARY MEDICINE AND IN COSMETICS | GALDERMA RES & DEV (FR) | 2004-08-25 | — | — | EP | claimed |
| US-6992094-B1 | Diarylselenide compounds and their use in human or veterinary medicine and in cosmetics | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2006-01-31 | — | — | US | disclosed |
| US-20060014803-A1 | Diarylselenide compounds and their use in human or veterinary medicine and in cosmetics | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2006-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060014803-A1 | Diarylselenide compounds and their use in human or veterinary medicine and in cosmetics | TYR, DERL1, GPX1 | CYP3A4 1847/4885CYP26A1 702/4885RARB 2125/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.