Known targets — ChEMBL curated mechanism
BTKCACNA1CCACNA1DCACNA1FCACNA1SCACNA2D1CACNA2D2DRD2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQHRH1HTR2AP2RY12
The experimentally established mechanism targets of Nitrogen. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.89 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.89 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | HTR6 | P50406 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | NT5E | P21589 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | MMP8 | P22894 | 1/20 | 0.48 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA3 | P07451 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nitrogen SCHEMBL3249439 | 0.97 | TSHR (0.84) | TSHRSMN1; SMN2POLBCYP2D6HTR6 | |
| Nitrogen SCHEMBL29220043 | 0.97 | TSHR (0.84) | TSHRSMN1; SMN2POLBCYP2D6HTR6 | |
| SCHEMBL30671620 | 0.94 | TSHR (1.00) | TSHRSMN1; SMN2POLBCYP2D6HTR6 | |
| Benzene SCHEMBL9751882 | 0.94 | TSHR (1.00) | TSHRSMN1; SMN2POLBCYP2D6HTR6 | |
| SCHEMBL30812783 | 0.94 | TSHR (1.00) | TSHRSMN1; SMN2POLBCYP2D6HTR6 | |
| SCHEMBL30307036 | 0.94 | TSHR (1.00) | TSHRSMN1; SMN2POLBCYP2D6HTR6 | |
| SCHEMBL2509 | 0.94 | TSHR (1.00) | TSHRSMN1; SMN2POLBCYP2D6HTR6 | |
| SCHEMBL3409457 | 0.94 | TSHR (1.00) | TSHRSMN1; SMN2POLBCYP2D6HTR6 | |
| SCHEMBL597672 | 0.94 | TSHR (1.00) | TSHRSMN1; SMN2POLBCYP2D6HTR6 | |
| SCHEMBL125188 | 0.94 | TSHR (1.00) | TSHRSMN1; SMN2POLBCYP2D6HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118058747-A | Flexible electrode, preparation method thereof and nerve interface | 中国科学院深圳先进技术研究院 | 2024-05-24 | — | — | CN | claimed |
| CN-114933538-A | Method for producing 2-methyl-4-aminophenol, and method for producing 2-methyl-4- (Boc-amino) -phenol | 八叶草健康产业研究院(厦门)有限公司 | 2022-08-23 | — | — | CN | claimed |
| CN-105385148-A | Sulfonated graphene-modified waterborne polyurethane resin and preparation method thereof | ZHEJIANG HUAFON SYNTHETIC RESIN CO LTD | 2016-03-09 | — | — | CN | claimed |
| CN-102276481-A | Calixarene derivative and metal complex thereof, and preparation method and application of calixarene derivative and metal complex thereof | — | 2011-12-14 | — | — | CN | claimed |
| CN-101503380-A | 5,11,17,23-tetra-sulfonic azo phenyl calyx [4] arene, and preparation and use thereof | UNIV SOOCHOW (CN) | 2009-08-12 | — | — | CN | claimed |
| CN-118058747-A | Flexible electrode, preparation method thereof and nerve interface | 中国科学院深圳先进技术研究院 | 2024-05-24 | — | — | CN | disclosed |
| CN-114933538-A | Method for producing 2-methyl-4-aminophenol, and method for producing 2-methyl-4- (Boc-amino) -phenol | 八叶草健康产业研究院(厦门)有限公司 | 2022-08-23 | — | — | CN | disclosed |
| CN-107607638-B | Method and kit for detecting aromatic compound | 杭州谱景柏泰科技有限公司 | 2020-06-12 | — | — | CN | disclosed |
| CN-111054392-A | Metal-solid acid double-center catalyst and application thereof in preparation of furfuryl alcohol by catalyzing xylose dehydration-hydrogenation | 山西大学 | 2020-04-24 | — | — | CN | disclosed |
| CN-105385148-A | Sulfonated graphene-modified waterborne polyurethane resin and preparation method thereof | ZHEJIANG HUAFON SYNTHETIC RESIN CO LTD | 2016-03-09 | — | — | CN | disclosed |
| CN-102276481-B | Calixarene derivative and metal complex thereof, and preparation method and application of calixarene derivative and metal complex thereof | UNIV SOOCHOW | 2014-05-14 | — | — | CN | disclosed |
| CN-102585540-B | Method for preparing edible pigment such as new red | SHANGHAI DYESTUFFS RES INST CO LTD | 2013-11-27 | — | — | CN | disclosed |
| CN-101618341-A | Carbon-based solid acid catalyst and preparation method thereof | NORTHWESTAGRICULTURE AND FORES | 2010-01-06 | — | — | CN | disclosed |
| CN-101503380-A | 5,11,17,23-tetra-sulfonic azo phenyl calyx [4] arene, and preparation and use thereof | UNIV SOOCHOW (CN) | 2009-08-12 | — | — | CN | disclosed |
| US-7105128-B2 | Comprises water-impermeable support, water-permeable layer and spreading layer having function of spreading liquid uniformly, wherein water-soluble indicator for colorimetry is incorporated into spreading layer | FUJI PHOTO FILM CO., LTD. (JP) | 2006-09-12 | — | — | US | disclosed |
| US-20030138352-A1 | Dry analytical element using water-soluble indicator for colorimetry | TANAKA HIDEAKI (JP) | 2003-07-24 | — | — | US | disclosed |
| US-20020071784-A1 | Dry analytical element and it's manufacturing method | FUJI PHOTO FILM CO., LTD. | 2002-06-13 | — | — | US | disclosed |
| US-5498551-A | COLORED LATEX PARTICLES | JANSSEN PHARMACEUTICA N.V. (BE) | 1996-03-12 | — | — | US | disclosed |
| US-4837168-A | QUALITATIVE, QUANTITATIVE ANALYSIS; VISUAL DETERMINATION | JANSSEN PHARMACEUTICA N.V. (BE) | 1989-06-06 | — | — | US | disclosed |
| EP-0227173-A2 | New method for the detection of specific binding agents and their corresponding bindable substances | JANSSEN PHARMACEUTICA N.V. (BE) | 1987-07-01 | — | — | EP | disclosed |