Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1071125 | 0.98 | GPR84 (0.44) | GPR84DAOHTR2AHTR6 | |
| SCHEMBL31171910 | 0.70 | EIF4A3 (0.43) | GPR84DAOCES2CES1 | |
| SCHEMBL7030237 | 0.68 | DAO (0.41) | GPR84DAO | |
| SCHEMBL45430 | 0.67 | CES2 (0.53) | GPR84DAOCES2CES1 | |
| SCHEMBL9545145 | 0.66 | KDM4E (0.44) | GPR84DAOCES2CES1 | |
| SCHEMBL6625805 | 0.65 | MAPT (0.44) | GPR84 | |
| SCHEMBL11355080 | 0.64 | CES2 (0.50) | GPR84DAOCES2CES1 | |
| Ammonia Solution, Strong SCHEMBL3047305 | 0.64 | CES2 (0.50) | GPR84DAOCES2CES1 | |
| SCHEMBL3975406 | 0.64 | CES2 (0.50) | GPR84DAOCES2CES1 | |
| SCHEMBL11050177 | 0.63 | ACHE (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060154889-A1 | Polyfluorinated nucleoside analogs and methods of use thereof | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2006-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060154889-A1 | Polyfluorinated nucleoside analogs and methods of use thereof | POLRMT, PCNA, POLL | GPR84 2217/4885DAO 1178/4885HTR2A 1087/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.