Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.38 |
| ▸ | TAS1R2 | Q8TE23 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11590180 | 1.00 | BDKRB1 (0.39) | BDKRB1TAS1R3TAS1R1TAS1R2HTT | |
| SCHEMBL11600503 | 0.83 | PTGDR2 (0.42) | BDKRB1TAS1R3TAS1R1TAS1R2HTT | |
| SCHEMBL11603441 | 0.83 | PTGDR2 (0.42) | BDKRB1TAS1R3TAS1R1TAS1R2HTT | |
| SCHEMBL11600497 | 0.83 | PTGDR2 (0.42) | BDKRB1TAS1R3TAS1R1TAS1R2HTT | |
| SCHEMBL11591514 | 0.80 | LMNA (0.47) | BDKRB1TAS1R3TAS1R1TAS1R2HTT | |
| SCHEMBL11591268 | 0.80 | KMT2A (0.41) | BDKRB1TAS1R3TAS1R1TAS1R2HTT | |
| SCHEMBL11589988 | 0.79 | KMT2A (0.51) | BDKRB1TAS1R3TAS1R1TAS1R2HTT | |
| SCHEMBL1265760 | 0.79 | MTNR1A (0.41) | BDKRB1TAS1R3TAS1R1TAS1R2HTT | |
| SCHEMBL15007184 | 0.79 | MTNR1A (0.41) | BDKRB1TAS1R3TAS1R1TAS1R2HTT | |
| SCHEMBL19215849 | 0.79 | MTNR1A (0.41) | BDKRB1TAS1R3TAS1R1TAS1R2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060194821-A1 | Compounds inhibiting the aggregation of superoxide dismutase-1 | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2006-08-31 | — | — | US | claimed |
| US-20060194821-A1 | Compounds inhibiting the aggregation of superoxide dismutase-1 | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2006-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060194821-A1 | Compounds inhibiting the aggregation of superoxide dismutase-1 | SOD1, SOD3, CAT | BDKRB1 4605/4885TAS1R3 4269/4885TAS1R1 3974/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.