Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 5/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.64 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.64 |
| ▸ | LMNA | P02545 | 4/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.64 |
| ▸ | HPGD | P15428 | 4/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.64 |
| ▸ | TTR | P02766 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | TP53 | P04637 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.64 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.64 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.64 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6036979 | 1.00 | CYP1A2 (0.64) | CYP1A2KDM4EPTGS1LMNACYP3A4 | |
| SCHEMBL9605438 | 0.83 | CYP1A1 (0.80) | CYP1A2KDM4EPTGS1LMNACYP3A4 | |
| SCHEMBL15901869 | 0.83 | CYP1A2 (0.61) | CYP1A2KDM4ECYP3A4CYP2C9HPGD | |
| SCHEMBL13907330 | 0.83 | CYP1A2 (0.61) | CYP1A2KDM4ECYP3A4CYP2C9HPGD | |
| SCHEMBL987852 | 0.81 | RAB9A (0.57) | CYP1A2KDM4EPTGS1LMNACYP3A4 | |
| SCHEMBL987851 | 0.81 | RAB9A (0.57) | CYP1A2KDM4EPTGS1LMNACYP3A4 | |
| SCHEMBL6853217 | 0.81 | ROCK2 (0.61) | CYP1A2KDM4ECYP3A4CYP2C9HPGD | |
| SCHEMBL6853224 | 0.81 | ROCK2 (0.61) | CYP1A2KDM4ECYP3A4CYP2C9HPGD | |
| SCHEMBL9126344 | 0.81 | LCK (0.64) | CYP1A2HPGDSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL9126350 | 0.81 | LCK (0.64) | CYP1A2HPGDSMN1; SMN2MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120172340-A1 | Compositions and Methods for Selectively Activating Human Sirtuins | BIOMOL INTERNATIONAL L.P. (US) | 2012-07-05 | — | — | US | disclosed |
| US-20060014705-A1 | Compositions and methods for selectively activating human sirtuins | BIOMOL INTERNATIONAL, INC. | 2006-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120172340-A1 | Compositions and Methods for Selectively Activating Human Sirtuins | SIRT1, SIRT7, SIRT5 | CYP1A2 4435/4885KDM4E 640/4885PTGS1 4289/4885 |
| US-20060014705-A1 | Compositions and methods for selectively activating human sirtuins | SIRT1, SIRT7, SIRT5 | CYP1A2 4435/4885KDM4E 640/4885PTGS1 4289/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.