Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | APP | P05067 | 6/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.56 |
| ▸ | CA12 | O43570 | 2/20 | 0.56 |
| ▸ | CA1 | P00915 | 2/20 | 0.56 |
| ▸ | CA2 | P00918 | 2/20 | 0.56 |
| ▸ | CA3 | P07451 | 2/20 | 0.56 |
| ▸ | CA4 | P22748 | 2/20 | 0.56 |
| ▸ | CA6 | P23280 | 2/20 | 0.56 |
| ▸ | CA5A | P35218 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL987851 | 1.00 | RAB9A (0.57) | RAB9AKMT2AAPPSMN1; SMN2MAPT | |
| SCHEMBL9804661 | 0.93 | CYP3A4 (0.52) | RAB9AKMT2AAPPSMN1; SMN2MAPT | |
| SCHEMBL9966009 | 0.87 | MAPT (0.65) | RAB9AKMT2ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL135604 | 0.87 | MAPT (0.65) | RAB9AKMT2ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL9678787 | 0.84 | APP (0.74) | RAB9AKMT2AAPPSMN1; SMN2MAPT | |
| Trans-4,4'-Dihydroxystilbene SCHEMBL491346 | 0.84 | APP (0.74) | RAB9AKMT2AAPPSMN1; SMN2MAPT | |
| SCHEMBL138489 | 0.84 | MAPT (0.61) | RAB9AKMT2ASMN1; SMN2MAPTNPC1 | |
| Trans-4,4'-Dihydroxystilbene SCHEMBL145659 | 0.84 | APP (0.74) | RAB9AKMT2AAPPSMN1; SMN2MAPT | |
| SCHEMBL6266983 | 0.84 | APP (0.74) | RAB9AKMT2AAPPSMN1; SMN2MAPT | |
| Trans-4,4'-Dihydroxystilbene SCHEMBL13339135 | 0.84 | APP (0.74) | RAB9AKMT2AAPPSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108863911-B | Preparation method and application of turn-on type mercury ion fluorescent probe | 山西大学 | 2020-07-10 | — | — | CN | claimed |
| WO-2011017916-A1 | SOLVATOCHROMIC FUNCTIONAL MONOMER AND USE THEREOF FOR CHEMOSENSING BY SOLVATOCHROMIC MOLECULAR IMPRINTING | CITY UNIVERSITY OF HONG KONG (CN) | 2011-02-17 | — | — | WO | claimed |
| US-20110003397-A1 | Solvatochromic functional monomer and the use thereof for chemosensing by solvatochromic molecular imprinting | CITY UNIVERSITY OF HONG KONG (HK) | 2011-01-06 | — | — | US | claimed |
| EP-1161555-B1 | 4-(4-HYDROXYSTYRYL)PYRIDINE-CONTAINING SUBSTRATES FOR AN ANALYTE DEPENDENT ENZYME ACTIVATION SYSTEM | PERKINELMER LAS INC (US) | 2008-01-02 | — | — | EP | claimed |
| WO-2006078941-A2 | NOVEL SIRTUIN ACTIVATING COMPOUNDS AND METHODS OF USE THEREOF | SIRTRIS PHARMACEUTICALS, INC. (US) | 2006-07-27 | — | — | WO | claimed |
| EP-1161555-A4 | 4-(4-HYDROXYSTYRYL)PYRIDINE-CONTAINING SUBSTRATES FOR AN ANALYTE DEPENDENT ENZYME ACTIVATION SYSTEM | NEN LIFE SCIENCE PROD INC (US) | 2004-12-22 | — | — | EP | claimed |
| JP-2003524768-A | — | — | 2003-08-19 | — | — | JP | claimed |
| US-6355443-B1 | 4-(4-hydroxystyryl) pyridine-containing substrates for an analyte dependent enzyme activation system | BOBROW MARK NORMAN (US) | 2002-03-12 | — | — | US | claimed |
| WO-2000055358-A9 | 4-(4-HYDROXYSTYRYL)PYRIDINE-CONTAINING SUBSTRATES FOR AN ANALYTE DEPENDENT ENZYME ACTIVATION SYSTEM | NEN LIFE SCIENCE PROD INC (US) | 2002-01-03 | — | — | WO | claimed |
| EP-1161555-A1 | 4-(4-HYDROXYSTYRYL)PYRIDINE-CONTAINING SUBSTRATES FOR AN ANALYTE DEPENDENT ENZYME ACTIVATION SYSTEM | NEN Life Science Products, Inc. (US) | 2001-12-12 | — | — | EP | claimed |
| WO-2000055358-A1 | 4-(4-HYDROXYSTYRYL)PYRIDINE-CONTAINING SUBSTRATES FOR AN ANALYTE DEPENDENT ENZYME ACTIVATION SYSTEM | NEN LIFE SCIENCE PRODUCTS, INC. (US) | 2000-09-21 | — | — | WO | claimed |
| CN-108863911-B | Preparation method and application of turn-on type mercury ion fluorescent probe | 山西大学 | 2020-07-10 | — | — | CN | disclosed |
| CN-108863911-B | Preparation method and application of turn-on type mercury ion fluorescent probe | 山西大学 | 2020-07-10 | — | — | CN | disclosed |
| US-8338553-B2 | Solvatochromic molecularly imprinted polymer for chemosensing | CITY UNIVERSITY OF HONG KONG (HK) | 2012-12-25 | — | — | US | disclosed |
| US-20120135091-A1 | METHODS AND COMPOSITIONS FOR ENHANCING LIFESPAN INVOLVING SIRTUIN-MODULATING COMPOUNDS AND CHALCOGENIDES | US ARMY, SECRETARY OF THE ARMY | 2012-05-31 | — | — | US | disclosed |
| EP-0559695-B1 | NEW PYRIDINE DERIVATIVES, METHODS OF PREPARING THEM AND THEIR USE AS DRUGS | BOEHRINGER MANNHEIM GMBH (DE) | 1997-01-22 | — | — | EP | disclosed |
| US-5399575-A | Antiallergens | BOEHRINGER MANNHEIM GMBH (DE) | 1995-03-21 | — | — | US | disclosed |
| EP-0559695-A1 | NEW PYRIDINE DERIVATIVES, METHODS OF PREPARING THEM AND THEIR USE AS DRUGS. | BOEHRINGER MANNHEIM GMBH (DE) | 1993-09-15 | — | — | EP | disclosed |
| WO-1992009598-A1 | NEW PYRIDINE DERIVATIVES, METHODS OF PREPARING THEM AND THEIR USE AS DRUGS | BOEHRINGER MANNHEIM GMBH (DE) | 1992-06-11 | — | — | WO | disclosed |
| US-4444868-A | CONTAINING STYRYL-TYPE NITROGEN-HETEROCYCLE RESIDUE POLYMER AND ACID | AGENCY OF INDUSTRIAL SCIENCE & TECHNOLOGY (JP) | 1984-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110003397-A1 | Solvatochromic functional monomer and the use thereof for chemosensing by solvatochromic molecular imprinting | CMKLR2, CMKLR1, CCR3 | RAB9A 4401/4885KMT2A 3911/4885APP 4363/4885 |
| US-20120135091-A1 | METHODS AND COMPOSITIONS FOR ENHANCING LIFESPAN INVOLVING SIRTUIN-MODULATING COMPOUNDS AND CHALCOGENIDES | HSF1, SIRT1, SIRT2 | RAB9A 1630/4885KMT2A 2312/4885APP 1811/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.