Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.37 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.34 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.34 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.33 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.33 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.33 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.33 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.33 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.33 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.33 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.33 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.33 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.33 |
| ▸ | PSMB4 | P28070 | 1/20 | 0.33 |
| ▸ | PSMB6 | P28072 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL853182 | 0.82 | ALDH1A1 (0.42) | ALDH1A1TSHRMAPK1TDP1LMNA | |
| SCHEMBL2933109 | 0.80 | HDAC3 (0.46) | ALDH1A1TSHRMAPK1TDP1ZDHHC20 | |
| SCHEMBL2933508 | 0.77 | ZDHHC20 (0.50) | ALDH1A1TSHRMAPK1ZDHHC20ZDHHC2 | |
| SCHEMBL9156920 | 0.76 | TSHR (0.50) | ALDH1A1TSHRMAPK1TDP1LMNA | |
| SCHEMBL28966764 | 0.76 | TSHR (0.41) | ALDH1A1TSHRMAPK1TDP1ZDHHC20 | |
| SCHEMBL29111068 | 0.75 | PSMB11 (0.37) | ALDH1A1TSHRMAPK1TDP1LMNA | |
| SCHEMBL2931470 | 0.75 | FAAH (0.55) | ALDH1A1TSHRMAPK1ZDHHC20ZDHHC2 | |
| SCHEMBL19409179 | 0.75 | MAPK1 (0.47) | ALDH1A1TSHRMAPK1TDP1ZDHHC20 | |
| SCHEMBL2932979 | 0.75 | — | — | |
| SCHEMBL3628039 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1718341-A2 | ARTICLES COMPRISING MAGNETIC MATERIAL AND BIOACTIVE AGENTS | Alnis Biosciences, Inc. (US) | 2006-11-08 | — | — | EP | disclosed |
| WO-2005070471-A2 | ARTICLES COMPRISING MAGNETIC MATERIAL AND BIOACTIVE AGENTS | ALNIS BIOSCIENCES, INC. (US) | 2005-08-04 | — | — | WO | disclosed |
| US-20050129769-A1 | Polymeric articles for carrying therapeutic agents | ALNIS BIOSCIENCES, INC. | 2005-06-16 | — | — | US | disclosed |
| EP-1531868-A2 | THERAPEUTIC AGENT-CONTAINING POLYMERIC NANOARTICLES | Alnis Biosciences, Inc. (US) | 2005-05-25 | — | — | EP | disclosed |
| WO-2005027873-A2 | THERAPEUTIC AMINOGLYCOSIDE-CONTAINING HYDROGEL NANOPARTICLES | ALNIS BIOSCIENCES, INC. (US) | 2005-03-31 | — | — | WO | disclosed |
| WO-2003101425-A2 | THERAPEUTIC AGENT-CONTAINING POLYMERIC NANOARTICLES | ALNIS BIOSCIENCES, INC. (US) | 2003-12-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050129769-A1 | Polymeric articles for carrying therapeutic agents | CD44, EPCAM, CLTB | ALDH1A1 3816/4885TSHR 1664/4885MAPK1 4417/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.