SCHEMBL2931470

SCHEMBL2931470

C=CC(=O)NC(=O)CCCCC

nearest known ligand 0.55

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
FAAH O00519 6/20 0.55
ZDHHC20 Q5W0Z9 1/20 0.53
ZDHHC2 Q9UIJ5 1/20 0.53
KMT2A Q03164 3/20 0.50
MEN1 O00255 2/20 0.50
MAPK1 P28482 1/20 0.50
HSP90AA1 P07900 1/20 0.50
MAPT P10636 4/20 0.47
ALDH1A1 P00352 2/20 0.47
TRPA1 O75762 1/20 0.46
POLB P06746 1/20 0.44
POLA1 P09884 1/20 0.44
KDM4E B2RXH2 2/20 0.43
CES2 O00748 1/20 0.43
CES1 P23141 1/20 0.43
NPSR1 Q6W5P4 1/20 0.42
PKM P14618 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
TSHR P16473 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15129341 0.98 FAAH (0.58) FAAHZDHHC20ZDHHC2KMT2AMEN1
SCHEMBL5830307 0.98 FAAH (0.58) FAAHZDHHC20ZDHHC2KMT2AMEN1
SCHEMBL7710247 0.98 FAAH (0.58) FAAHZDHHC20ZDHHC2KMT2AMEN1
SCHEMBL7710254 0.98 FAAH (0.58) FAAHZDHHC20ZDHHC2KMT2AMEN1
SCHEMBL4919984 0.98 FAAH (0.58) FAAHZDHHC20ZDHHC2KMT2AMEN1
SCHEMBL3211607 0.98 FAAH (0.58) FAAHZDHHC20ZDHHC2KMT2AMEN1
SCHEMBL2933508 0.94 ZDHHC20 (0.50) FAAHZDHHC20ZDHHC2KMT2AMEN1
SCHEMBL5066977 0.90 HRH3 (0.55) FAAHKMT2AMEN1MAPTPOLB
SCHEMBL7718955 0.90 HRH3 (0.55) FAAHKMT2AMEN1MAPTPOLB
SCHEMBL2933109 0.85 HDAC3 (0.46) FAAHZDHHC20ZDHHC2KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7732550-B2 Stimuli-responsive polymer utilizing keto-enol tautomerization and stimuli-responsive separating material and chemical-releasing capsule comprising the same AGENCY OF INDUSTRIAL SCIENCE & TECHNOLOGY MITI (JP) 2010-06-08 US disclosed
EP-0922715-B1 Stimuli-responsive polymer utilizing keto-enol tautomerization AGENCY IND SCIENCE TECHN (JP) 2008-04-02 EP disclosed
US-6858694-B2 Stimuli-responsive polymer utilizing keto-enol tautomerization and stimuli-responsive separating material and chemical-releasing capsule comprising the same AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY MITI (JP) 2005-02-22 US disclosed
US-6852819-B2 Stimuli-responsive polymer utilizing keto-enol tautomerization and stimuli-responsive separating material and chemical-releasing capsule comprising the same AGENCY OF INDUSTRIAL SCIENCE & TECHNOLOGY MITI (JP) 2005-02-08 US disclosed
US-20040223947-A1 Stimuli-responsive polymer utilizing keto-enol tautomerization and stimuli-responsive separating material and chemical-releasing capsule comprising the same JNC CORPORATION (JP) 2004-11-11 US disclosed
US-20040223945-A1 Stimuti-responsive polymer utilizing keto-enol tautomerization and stimuli-responsive separating material and chemical-releasing capsule comprising the same JNC CORPORATION (JP) 2004-11-11 US disclosed
US-20020188084-A1 Stimuli-responsive polymer utilizing keto-enol tautomerization and stimuli-responsive separating material and chemical-releasing capsule comprising the same JNC CORPORATION (JP) 2002-12-12 US disclosed
EP-0922715-A2 Stimuli-responsive polymer utilizing keto-enol tautomerization AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY MITI (JP) 1999-06-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040223945-A1 Stimuti-responsive polymer utilizing keto-enol tautomerization and stimuli-responsive separating material and chemical-releasing capsule comprising the same CREB1, STIM2, GABRE FAAH 1163/4885ZDHHC20 3277/4885ZDHHC2 3156/4885
US-20040223947-A1 Stimuli-responsive polymer utilizing keto-enol tautomerization and stimuli-responsive separating material and chemical-releasing capsule comprising the same ACMSD, ADSL, CREB1 FAAH 1057/4885ZDHHC20 3314/4885ZDHHC2 3078/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.