Lysine

Lysine

SCHEMBL6037599

NCCCC[C@H](N)C(=O)[O-].[Li+]

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Lysine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ GSR P00390 1/20 0.61
▸ RNPEP Q9H4A4 1/20 0.43
▸ GNAI3 P08754 1/20 0.43
▸ GNAO1 P09471 1/20 0.43
▸ GNAI1 P63096 1/20 0.43
▸ DPP7 Q9UHL4 9/20 0.42
▸ DPP8 Q6V1X1 5/20 0.42
▸ DPP9 Q86TI2 5/20 0.42
▸ DPP4 P27487 3/20 0.42
▸ CPB2 Q96IY4 2/20 0.39
▸ FAP Q12884 1/20 0.38
▸ MMP2 P08253 1/20 0.37
▸ ARG1 P05089 1/20 0.36
▸ ARG2 P78540 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Lysine SCHEMBL27164815 1.00 GSR (0.61) GSRRNPEPGNAI3GNAO1GNAI1
Lysine SCHEMBL4400353 0.95 GSR (0.61) GSRRNPEPGNAI3GNAO1GNAI1
Lysine SCHEMBL5691386 0.95 GSR (0.61) GSRRNPEPGNAI3GNAO1GNAI1
Lysine SCHEMBL5691382 0.95 GSR (0.61) GSRRNPEPGNAI3GNAO1GNAI1
Lysine SCHEMBL5062296 0.95 GSR (0.61) GSRRNPEPGNAI3GNAO1GNAI1
Lysine SCHEMBL25283016 0.95 GSR (0.61) GSRRNPEPGNAI3GNAO1GNAI1
Lysine SCHEMBL3517540 0.95 GSR (0.61) GSRRNPEPGNAI3GNAO1GNAI1
Lysine SCHEMBL121844 0.95 GSR (0.61) GSRRNPEPGNAI3GNAO1GNAI1
Lysine SCHEMBL3739868 0.95 GSR (0.61) GSRRNPEPGNAI3GNAO1GNAI1
Lysine SCHEMBL3749535 0.95 GSR (0.61) GSRRNPEPGNAI3GNAO1GNAI1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260042080-A1 SOLID SORBENT FOR REMOVAL OF CARBON DIOXIDE FROM A CO2-CONTAINING GAS SUSTAERA INC (US) 2026-02-12 — — US claimed
EP-4651974-A2 SOLID SORBENT FOR REMOVAL OF CARBON DIOXIDE FROM A CO2-CONTAINING GAS Sustaera Inc. (US) 2025-11-26 — — EP claimed
WO-2024155658-A2 SOLID SORBENT FOR REMOVAL OF CARBON DIOXIDE FROM A CO2-CONTAINING GAS SUSTAERA INC. (US) 2024-07-25 — — WO claimed
CN-108774316-B Cationic polyarylether resin, seperation film and preparation method thereof 四川大学 2019-07-12 — — CN claimed
CN-108774316-A Cationic polyarylether resin, seperation film and preparation method thereof 四川大学 2018-11-09 — — CN claimed
US-20260042080-A1 SOLID SORBENT FOR REMOVAL OF CARBON DIOXIDE FROM A CO2-CONTAINING GAS SUSTAERA INC (US) 2026-02-12 — — US disclosed
US-20260042080-A1 SOLID SORBENT FOR REMOVAL OF CARBON DIOXIDE FROM A CO2-CONTAINING GAS SUSTAERA INC (US) 2026-02-12 — — US disclosed
EP-4651974-A2 SOLID SORBENT FOR REMOVAL OF CARBON DIOXIDE FROM A CO2-CONTAINING GAS Sustaera Inc. (US) 2025-11-26 — — EP disclosed
EP-4651974-A2 SOLID SORBENT FOR REMOVAL OF CARBON DIOXIDE FROM A CO2-CONTAINING GAS Sustaera Inc. (US) 2025-11-26 — — EP disclosed
WO-2024155658-A3 SOLID SORBENT FOR REMOVAL OF CARBON DIOXIDE FROM A CO2-CONTAINING GAS SUSTAERA INC. (US) 2024-10-10 — — WO disclosed
WO-2024155658-A2 SOLID SORBENT FOR REMOVAL OF CARBON DIOXIDE FROM A CO2-CONTAINING GAS SUSTAERA INC. (US) 2024-07-25 — — WO disclosed
WO-2024155658-A2 SOLID SORBENT FOR REMOVAL OF CARBON DIOXIDE FROM A CO2-CONTAINING GAS SUSTAERA INC. (US) 2024-07-25 — — WO disclosed
CN-113087003-B Carbon dioxide absorption and utilization method and application thereof 国家能源投资集团有限责任公司 2022-12-09 — — CN disclosed
CN-113087003-A Carbon dioxide absorption and utilization method and application thereof 国家能源投资集团有限责任公司 2021-07-09 — — CN disclosed
CN-108774316-B Cationic polyarylether resin, seperation film and preparation method thereof 四川大学 2019-07-12 — — CN disclosed
CN-108774316-A Cationic polyarylether resin, seperation film and preparation method thereof 四川大学 2018-11-09 — — CN disclosed
CN-101913237-B Manufacturing method of high-temperature resistant and corrosion-resistant polyphenyl thioether composite tube CHEN XUN 2013-03-27 — — CN disclosed
CN-101913237-A Manufacturing method of high-temperature resistant and corrosion-resistant polyphenyl thioether composite tube XUN CHEN 2010-12-15 — — CN disclosed
US-20060183888-A1 Pyrrolysine synthesis and modification NIH - DEITR 2006-08-17 — — US disclosed
US-20060166319-A1 Charging tRNA with pyrrolysine NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2006-07-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060183888-A1 Pyrrolysine synthesis and modification PTMS, QPCTL, DNPEP GSR 4294/4885RNPEP 185/4885GNAI3 3491/4885
US-20260042080-A1 SOLID SORBENT FOR REMOVAL OF CARBON DIOXIDE FROM A CO2-CONTAINING GAS SLC6A6, SLC6A19, SLC6A9 GSR 1440/4885RNPEP 1842/4885GNAI3 1836/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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