SCHEMBL6038127

SCHEMBL6038127

OC[C@H]1OC=C[C@](O)(Cc2ccccc2)[C@@]1(O)Cc1ccccc1

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.32
HSD11B1 P28845 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL630148 0.71 TDP1 (0.33) TDP1TSHR
SCHEMBL8883781 0.69 HSD11B1 (0.35) TDP1HSD11B1TSHR
SCHEMBL2785293 0.68 ALDH1A1 (0.32) TSHR
SCHEMBL9094336 0.68 ALDH1A1 (0.32) TSHR
SCHEMBL9620579 0.67 TSHR (0.31) TSHR
SCHEMBL629678 0.65 CYP3A4 (0.40) TDP1HSD11B1TSHR
SCHEMBL16148070 0.65 PTGS2 (0.34) TSHR
SCHEMBL7641953 0.63 TSHR (0.38) TDP1TSHR
SCHEMBL9096127 0.63 TSHR (0.38) TDP1TSHR
SCHEMBL4024047 0.63 GRIN2D (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026107431-A1 STEREOSELECTIVE SYNTHESIS OF L,2-CIS-2-AMINOGLYCOSIDES BRANDEIS UNIVERSITY (US) 2026-05-21 WO disclosed
US-7102023-B2 Protecting groups useful in the synthesis of polysaccharides, natural products, and combinatorial libraries MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2006-09-05 US disclosed
US-20040220389-A1 Protecting groups useful in the synthesis of polysaccharides, natural products, and combinatorial libraries NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2004-11-04 US disclosed
US-6693178-B2 HALOGENATED BENZYL ETHER GALACTOPYRANOSIDE, GLUCOPYRANOSIDE, RIBOFURANOSIDE OR XYLOFURANOSIDE DERIVATIVES; STABLE, EASILY REMOVED MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2004-02-17 US disclosed
US-20030181690-A1 Protecting groups useful in the synthesis of polysaccharides, natural products, and combinatorial libraries NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2003-09-25 US disclosed
EP-1233970-A2 PROTECTING GROUPS USEFUL IN THE SYNTHESIS OF POLYSACCHARIDES, NATURAL PRODUCTS, AND COMBINATORIAL LIBRARIES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2002-08-28 EP disclosed
US-6426421-B1 HALOGENATED BENZYL ETHER-BASED PROTECTING GROUPS FOR FUNCTIONAL GROUPS, OF ALCOHOLS, THIOLS, AMINES, CARBOXYLIC ACIDS, AND PHOSPHORIC ACIDS MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2002-07-30 US disclosed
WO-2001038337-A2 PROTECTING GROUPS USEFUL IN THE SYNTHESIS OF POLYSACCHARIDES, NATURAL PRODUCTS, AND COMBINATORIAL LIBRARIES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2001-05-31 WO disclosed
US-5679769-A SOLID PHASE SYNTHESIS OF OLIGOSACCHARIDES-OLIGOPEPTIDES; ANTICARCINOGENIC AGENTS SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) 1997-10-21 US disclosed
WO-1996040198-A1 SYNTHESIS OF ASPARAGINE-LINKED GLYCOPEPTIDES ON A POLYMERIC SOLID SUPPORT SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) 1996-12-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040220389-A1 Protecting groups useful in the synthesis of polysaccharides, natural products, and combinatorial libraries FUT5, FUT6, UGCG TDP1 3894/4885HSD11B1 1552/4885TSHR 2453/4885
US-20030181690-A1 Protecting groups useful in the synthesis of polysaccharides, natural products, and combinatorial libraries FUT5, FUT6, UGCG TDP1 3894/4885HSD11B1 1552/4885TSHR 2453/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.