Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.56 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.56 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.56 |
| ▸ | SRD5A2 | P31213 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | NOS1 | P29475 | 3/20 | 0.43 |
| ▸ | NOS3 | P29474 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10072447 | 0.91 | ALDH1A1 (0.64) | ADRA2AADRA2BADRA2CSRD5A2LMNA | |
| SCHEMBL10440818 | 0.91 | LMNA (0.68) | ADRA2AADRA2BADRA2CSRD5A2LMNA | |
| SCHEMBL21300034 | 0.85 | CYP3A4 (0.45) | ADRA2AADRA2BADRA2CSRD5A2LMNA | |
| SCHEMBL2605733 | 0.81 | ALDH1A1 (0.46) | ADRA2AADRA2BADRA2CMAPTPKM | |
| SCHEMBL92849 | 0.81 | TSHR (0.63) | SRD5A2ALDH1A1KMT2ATP53TSHR | |
| SCHEMBL13746337 | 0.80 | PLK1 (0.51) | ADRA2AADRA2BADRA2CLMNAMAPT | |
| SCHEMBL14699617 | 0.80 | MAPT (0.55) | ADRA2AADRA2BADRA2CLMNAMAPT | |
| SCHEMBL27252008 | 0.80 | ALDH1A1 (0.50) | ADRA2AADRA2BADRA2CMAPTPKM | |
| SCHEMBL6299007 | 0.79 | NOS1 (0.59) | ADRA2AADRA2BADRA2CLMNAMAPT | |
| SCHEMBL17733133 | 0.79 | HDAC3 (0.47) | ADRA2AADRA2BADRA2CMAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017212059-A1 | SYNTHESIS OF PHOTOACTIVABLE CAGED CYCLOFEN-OH AND DERIVATIVES THEREOF | PARIS SCIENCES ET LETTRES - QUARTIER LATIN (FR) | 2017-12-14 | — | — | WO | disclosed |
| EP-3225645-A1 | PHOTOACTIVE ADDITIVES WITH PHOTOACTIVE MONOMERS AND ENDCAPS | SABIC Global Technologies B.V. (NL) | 2017-10-04 | — | — | EP | disclosed |
| US-20060210452-A1 | Very large scale immobilized polymer synthesis | AFFYMAX TECHNOLOGIES, N.V., A NETHERLANDS ANTILLES CORPORATION | 2006-09-21 | — | — | US | disclosed |
| US-20060194258-A1 | Polypeptide array synthesis | AFFYMETRIX, INC. (US) | 2006-08-31 | — | — | US | disclosed |
| US-7087732-B2 | Nucleotides and analogs having photoremovable protecting groups | AFFYMETRIX, INC. (US) | 2006-08-08 | — | — | US | disclosed |
| US-6955915-B2 | Apparatus comprising polymers | AFFYMETRIX, INC. (US) | 2005-10-18 | — | — | US | disclosed |
| US-20050208537-A1 | Very large scale immobilized polymer synthesis | AFFYMETRIX, INC. (US) | 2005-09-22 | — | — | US | disclosed |
| US-6919211-B1 | Polypeptide arrays | AFFYMETRIX, INC. (US) | 2005-07-19 | — | — | US | disclosed |
| US-20050153362-A1 | Polymer arrays | PIRRUNG MICHAEL C (US) | 2005-07-14 | — | — | US | disclosed |
| US-20050153363-A1 | Polymer arrays | PIRRUNG MICHAEL C (US) | 2005-07-14 | — | — | US | disclosed |
| US-5889165-A | Photolabile nucleoside protecting groups | AFFYMETRIX, INC. (US) | 1999-03-30 | — | — | US | disclosed |
| US-5753788-A | Photolabile nucleoside protecting groups | AFFYMETRIX, INC. (US) | 1998-05-19 | — | — | US | disclosed |
| US-5744305-A | Arrays of materials attached to a substrate | AFFYMETRIX, INC. (US) | 1998-04-28 | — | — | US | disclosed |
| US-5744101-A | Photolabile nucleoside protecting groups | AFFYMAX TECHNOLOGIES N.V. (GB) | 1998-04-28 | — | — | US | disclosed |
| US-5489678-A | 6-NITRO-1,3-BENZOXAZOL-5-YL ALKYLOXY PROTECTIVE GROUP ON THE 5' POSITION OF A DEOXYNUCLEOSIDE; COMPUTERIZED SOLID PHASE SYNTHESIS | AFFYMAX TECHNOLOGIES N.V. (NL) | 1996-02-06 | — | — | US | disclosed |
| US-5424186-A | Biosynthesis of oligonucleotides on solid substrate by irradiation of predefined segments to remove blocking agents; then coupling with nucleotide | AFFYMAX TECHNOLOGIES N.V. (AN) | 1995-06-13 | — | — | US | disclosed |
| WO-1994010128-A1 | NOVEL PHOTOREACTIVE PROTECTING GROUPS | AFFYMAX TECHNOLOGIES N.V. (AN) | 1994-05-11 | — | — | WO | disclosed |
| EP-0562025-A4 | — | — | 1994-03-30 | — | — | EP | disclosed |
| EP-0562025-A1 | VERY LARGE SCALE IMMOBILIZED POLYMER SYNTHESIS | AFFYMAX TECHNOLOGIES N.V. (AN) | 1993-09-29 | — | — | EP | disclosed |
| WO-1992010092-A1 | VERY LARGE SCALE IMMOBILIZED POLYMER SYNTHESIS | AFFYMAX TECHNOLOGIES N.V. (AN) | 1992-06-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060194258-A1 | Polypeptide array synthesis | MRPL21, NGLY1, PSAP | ADRA2A 4788/4885ADRA2B 4716/4885ADRA2C 4741/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.