SCHEMBL10072447

SCHEMBL10072447

O=Nc1ccc(C(=O)c2ccccc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.64
SRD5A2 P31213 2/20 0.60
TDP1 Q9NUW8 2/20 0.54
L3MBTL1 Q9Y468 2/20 0.54
ATM Q13315 1/20 0.54
KMT2A Q03164 6/20 0.53
PKM P14618 1/20 0.53
CASP3 P42574 1/20 0.53
SENP7 Q9BQF6 1/20 0.53
SENP6 Q9GZR1 1/20 0.53
MEN1 O00255 5/20 0.52
RAB9A P51151 4/20 0.52
MAPT P10636 2/20 0.52
LMNA P02545 1/20 0.52
MAPK13 O15264 1/20 0.52
MAPK12 P53778 1/20 0.52
MAPK11 Q15759 1/20 0.52
MAPK14 Q16539 1/20 0.52
NPC1 O15118 3/20 0.50
HPGD P15428 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6038454 0.91 ADRA2A (0.56) ALDH1A1SRD5A2KMT2APKMCASP3
SCHEMBL28845433 0.86 CES2 (0.68) ALDH1A1TDP1KMT2APKMCASP3
SCHEMBL314267 0.83 ALDH1A1 (0.93) ALDH1A1SRD5A2TDP1L3MBTL1ATM
SCHEMBL9066312 0.83 ALDH1A1 (0.93) ALDH1A1SRD5A2TDP1L3MBTL1ATM
SCHEMBL10440818 0.82 LMNA (0.68) ALDH1A1SRD5A2TDP1L3MBTL1KMT2A
SCHEMBL29042750 0.82 TRPA1 (0.72) ALDH1A1SRD5A2TDP1L3MBTL1ATM
SCHEMBL28848196 0.82 TRPA1 (0.72) ALDH1A1SRD5A2TDP1L3MBTL1ATM
SCHEMBL28672503 0.80 ALDH1A1 (0.61) ALDH1A1SRD5A2TDP1L3MBTL1ATM
SCHEMBL13191412 0.80 ALDH1A1 (0.61) ALDH1A1SRD5A2TDP1L3MBTL1ATM
Benzophenone SCHEMBL1404019 0.80 ALDH1A1 (0.88) ALDH1A1SRD5A2TDP1L3MBTL1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250066284-A1 PHOTOPOLYMERIZATION INITIATORS AND THEIR USE UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 2025-02-27 US disclosed
US-20150232614-A1 BLENDS CONTAINING PHOTOACTIVE ADDITIVE SABIC GLOBAL TECHNOLOGIES B.V. 2015-08-20 US disclosed
US-20120046384-A2 PHOTOACTIVATABLE CROSSLINKER SURMODICS, INC. (US) 2012-02-23 US disclosed
US-20100232830-A1 PHTHALOCYANINE CRYSTAL, AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE AND IMAGE-FORMING DEVICE USING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2010-09-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120046384-A2 PHOTOACTIVATABLE CROSSLINKER GLO1, LCP1, PLOD1 ALDH1A1 1430/4885SRD5A2 2458/4885TDP1 1319/4885
US-20250066284-A1 PHOTOPOLYMERIZATION INITIATORS AND THEIR USE PPOX, CCNI, DHPS ALDH1A1 188/4885SRD5A2 1858/4885TDP1 2170/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.