SCHEMBL6038482

SCHEMBL6038482

[NH]S(=O)(=O)c1cc(Cl)c(Cl)cc1Cl

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.44
GUSB P08236 1/20 0.38
CA12 O43570 4/20 0.37
CA1 P00915 4/20 0.37
CA2 P00918 4/20 0.37
CA9 Q16790 4/20 0.37
CA3 P07451 3/20 0.37
CA4 P22748 3/20 0.37
CA6 P23280 3/20 0.37
CA5A P35218 3/20 0.37
CA7 P43166 3/20 0.37
CA14 Q9ULX7 3/20 0.37
CA5B Q9Y2D0 3/20 0.37
CA13 Q8N1Q1 2/20 0.36
CISD1 Q9NZ45 1/20 0.36
PGR P06401 1/20 0.36
CNR1 P21554 1/20 0.36
CDK1 P06493 1/20 0.35
CCNB1 P14635 1/20 0.35
CCNA2 P20248 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3267601 0.81 HTT (0.47) L3MBTL1CA12CA1CA2CA9
SCHEMBL11859802 0.78 L3MBTL1 (0.47) L3MBTL1GUSBCA12CA1CA2
SCHEMBL30161536 0.76 TRPV4 (0.47) L3MBTL1GUSBCA12CA1CA2
SCHEMBL16756765 0.76 L3MBTL1 (0.45) L3MBTL1GUSBCA12CA1CA2
SCHEMBL534192 0.76 TRPV4 (0.47) L3MBTL1GUSBCA12CA1CA2
SCHEMBL11509219 0.75 ALDH1A1 (0.42) L3MBTL1GUSBCA12CA1CA2
SCHEMBL826419 0.74 L3MBTL1 (0.44) L3MBTL1GUSBCA12CA1CA2
SCHEMBL11684848 0.74 L3MBTL1 (0.44) L3MBTL1GUSBCA12CA1CA2
SCHEMBL11687192 0.74 L3MBTL1 (0.44) L3MBTL1GUSBCA12CA1CA2
SCHEMBL15461575 0.74 L3MBTL1 (0.48) L3MBTL1GUSBCA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060004010-A1 Ccr4 antagonist and medical use thereof ONO PHARMACEUTICAL CO., LTD. (JP) 2006-01-05 US disclosed
EP-1541563-A1 CCR4 ANTAGONIST AND MEDICINAL USE THEREOF ONO PHARMACEUTICAL CO., LTD. (JP) 2005-06-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060004010-A1 Ccr4 antagonist and medical use thereof CCR4, CCR1, CCR9 L3MBTL1 2666/4885GUSB 3326/4885CA12 667/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.