Hexanoyl-Coa

Hexanoyl-Coa

SCHEMBL60392

CCCCCC(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(=O)(O)OP(=O)(O)OC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1OP(=O)(O)O

nearest known ligand 0.88

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ NAA50 Q9GZZ1 2/20 0.86
▸ CHAT P28329 2/20 0.82
▸ EP300 Q09472 3/20 0.81
▸ KAT5 Q92993 2/20 0.81
▸ AURKA O14965 2/20 0.81
▸ KAT2B Q92831 1/20 0.81
▸ CREBBP Q92793 1/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hexanoyl-Coa SCHEMBL11940278 1.00 NAA50 (0.86) NAA50CHATEP300KAT5AURKA
Hexanoyl-Coa SCHEMBL21496009 1.00 NAA50 (0.86) NAA50CHATEP300KAT5AURKA
Octanoyl-Coa SCHEMBL2370508 0.99 NAA50 (0.85) NAA50CHATEP300KAT5AURKA
SCHEMBL11027446 0.99 NAA50 (0.85) NAA50CHATEP300KAT5AURKA
SCHEMBL2934083 0.99 NAA50 (0.85) NAA50CHATEP300KAT5AURKA
Decanoyl-Coa SCHEMBL24667667 0.99 NAA50 (0.85) NAA50CHATEP300KAT5AURKA
SCHEMBL1756475 0.99 NAA50 (0.85) NAA50CHATEP300KAT5AURKA
SCHEMBL20970006 0.99 NAA50 (0.85) NAA50CHATEP300KAT5AURKA
Octanoyl-Coa SCHEMBL24667663 0.99 NAA50 (0.85) NAA50CHATEP300KAT5AURKA
SCHEMBL1129961 0.99 NAA50 (0.85) NAA50CHATEP300KAT5AURKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1322 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12606853-B2 Production of short chain fatty acids Nourish Ingredients Pty Ltd (AU) 2026-04-21 — — US claimed
US-12540341-B2 Biosynthetic platform for the production of olivetolic acid and analogues of olivetolic acid THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-02-03 — — US claimed
US-20260028651-A1 METHOD OF PRODUCING & PROCESSING DIAMINES AGAIN BIO APS (DK) 2026-01-29 — — US claimed
EP-3998336-B1 MICROORGANISMS AND METHODS FOR PRODUCING CANNABINOIDS AND CANNABINOID DERIVATIVES UNIV CALIFORNIA (US) 2026-01-07 — — EP claimed
EP-4662192-A1 MICROORGANISMS AND METHODS FOR REDUCING BY-PRODUCTS Genomatica, Inc. (US) 2025-12-17 — — EP claimed
US-20250354180-A1 ENZYMES, CELLS, AND METHODS FOR PRODUCING CIS-3 HEXENOL MANUS BIO INC (US) 2025-11-20 — — US claimed
EP-4638753-A2 PRODUCTION OF CANNABINOIDS AND ENGINEERED CELLS THEREFOR Cellibre, Inc. (US) 2025-10-29 — — EP claimed
EP-4638509-A2 IMPROVED ENZYMES AND METHODS FOR THE SYNTHESIS OF CANNABINOIDS Cellibre, Inc. (US) 2025-10-29 — — EP claimed
US-12442026-B2 Production of fatty acyl-CoA in yeast using a fatty acid feedstock PYRONE SYSTEMS, INC. (US) 2025-10-14 — — US claimed
US-20250263758-A1 A CELL-FREE BIO-MANUFACTURING PLATFORM FOR PRODUCTION OF FATTY ACIDS AND CANNABINOIDS UNITED STATES DEPARTMENT OF ENERGY 2025-08-21 — — US claimed
US-20140186902-A1 METHODS OF PRODUCING 6-CARBON CHEMICALS VIA CoA-DEPENDENT CARBON CHAIN ELONGATION ASSOCIATED WITH CARBON STORAGE INVISTA NORTH AMERICA S. A R.L. (US) 2014-07-03 — — US claimed
WO-2014093865-A2 METHODS OF PRODUCING 6-CARBON CHEMICALS VIA CoA-DEPENDENT CARBON CHAIN ELONGATION ASSOCIATED WITH CARBON STORAGE INVISTA NORTH AMERICA S.A.R.L. (US) 2014-06-19 — — WO claimed
EP-2732037-A1 GENES AND PROTEINS FOR ALKANOYL-COA SYNTHESIS National Research Council of Canada (CA) 2014-05-21 — — EP claimed
US-20130183728-A1 METHODS OF PRODUCING 6-CARBON CHEMICALS VIA CoA-DEPENDENT CARBON CHAIN ELONGATION ASSOCIATED WITH CARBON STORAGE INVISTA NORTH AMERICA S.A R.L. (US) 2013-07-18 — — US claimed
WO-2013090837-A2 METHODS OF PRODUCING 6-CARBON CHEMICALS VIA CoA-DEPENDENT CARBON CHAIN ELONGATION ASSOCIATED WITH CARBON STORAGE INVISTA NORTH AMERICA S.A.R.L. (US) 2013-06-20 — — WO claimed
US-20130116462-A1 METHOD TO PRODUCE ACETYLDIACYLGLYCEROLS (AC-TAGS) BY EXPRESSION OF AN ACETYLTRANSFERASE GENE ISOLATED FROM EUONYMUS ALATUS (BURNING BUSH) BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2013-05-09 — — US claimed
WO-2013006953-A1 GENES AND PROTEINS FOR ALKANOYL-COA SYNTHESIS NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2013-01-17 — — WO claimed
WO-2011082253-A2 A METHOD TO PRODUCE ACETYLDIACYLGLYCEROLS (AC-TAGS) BY EXPRESSION OFAN ACETYLTRANSFERASE GENE ISOLATED FROM EUONYMUS ALATUS (BURNING BUSH) BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2011-07-07 — — WO claimed
US-7217557-B1 Three-dimensional structure of polyketide synthases THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 2007-05-15 — — US claimed
WO-2001007579-A2 METHODS AND COMPOSITIONS FOR DETERMINING ENZYMATIC ACTIVITY THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 2001-02-01 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12540341-B2 Biosynthetic platform for the production of olivetolic acid and analogues of olivetolic acid COASY, HPD, FADS2 NAA50 668/4885CHAT 1473/4885EP300 1683/4885
US-20260028651-A1 METHOD OF PRODUCING & PROCESSING DIAMINES DDC, DAO, ODC1 NAA50 69/4885CHAT 77/4885EP300 1948/4885
US-12606853-B2 Production of short chain fatty acids LCAT, FASN, ELOVL3 NAA50 71/4885CHAT 990/4885EP300 312/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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