Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | NAAA | Q02083 | 3/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8654542 | 0.97 | NAAA (0.49) | SMN1; SMN2NPC1RECQLRAB9ANAAA | |
| SCHEMBL8656130 | 0.94 | NAAA (0.39) | SMN1; SMN2NPC1RECQLRAB9ANAAA | |
| SCHEMBL10702694 | 0.80 | NAAA (0.47) | SMN1; SMN2NPC1RECQLRAB9ANAAA | |
| SCHEMBL3553273 | 0.74 | FAAH (0.42) | ALDH1A1 | |
| SCHEMBL7769683 | 0.71 | LMNA (0.64) | SMN1; SMN2NPC1RECQLRAB9ANAAA | |
| SCHEMBL7769682 | 0.71 | SMN1; SMN2 (0.61) | SMN1; SMN2NPC1RECQLRAB9ANAAA | |
| SCHEMBL6040251 | 0.71 | GRM5 (0.39) | NPC1LMNA | |
| SCHEMBL5761025 | 0.70 | HTR2C (0.46) | NAAALMNAALDH1A1 | |
| SCHEMBL7515003 | 0.70 | SIGMAR1 (0.55) | SMN1; SMN2NPC1RECQLRAB9ANAAA | |
| SCHEMBL5213750 | 0.70 | NPC1 (0.59) | SMN1; SMN2NPC1RECQLRAB9ANAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811576-A | 1-CARBOXY-2-LOWERALKYL-3,4,6-TRI(HALO)BENZENES; GRAMPOSITIVE AND-NEGATIVE BACTERIA; INFECTIONS; STERILIZATION OF MEDICAL EQUIPMENT | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1998-09-22 | — | — | US | disclosed |
| US-5723648-A | Intermediates for anti-microbial benzoheterocyclic compounds | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1998-03-03 | — | — | US | disclosed |