Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | THRB | P10828 | 4/20 | 0.47 |
| ▸ | PPARG | P37231 | 4/20 | 0.47 |
| ▸ | TTR | P02766 | 3/20 | 0.47 |
| ▸ | THRA | P10827 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.47 |
| ▸ | RXRA | P19793 | 2/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.47 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8187037 | 0.87 | THRB (0.67) | MEN1KMT2ATHRBPPARGTTR | |
| SCHEMBL25626909 | 0.81 | CA1 (0.41) | SIRT5THRBTHRACYP2C9NR3C1 | |
| SCHEMBL17479954 | 0.81 | THRB (0.44) | MEN1KMT2ATHRBPPARGTHRA | |
| SCHEMBL523988 | 0.81 | THRB (0.44) | MEN1KMT2ATHRBPPARGTHRA | |
| SCHEMBL8466203 | 0.80 | MEN1 (0.50) | MEN1KMT2ATHRBPPARGTTR | |
| SCHEMBL12808489 | 0.80 | PPARG (0.70) | MEN1KMT2ATHRBPPARGTTR | |
| SCHEMBL10397364 | 0.78 | PTPN1 (0.37) | SIRT5MEN1KMT2ATHRBPPARG | |
| SCHEMBL17618929 | 0.77 | THRB (0.47) | SIRT5MEN1KMT2ATHRBPPARG | |
| SCHEMBL14664240 | 0.76 | TAAR1 (0.52) | SIRT5MEN1KMT2ATHRBPPARG | |
| SCHEMBL12808490 | 0.76 | PCNA (0.68) | MEN1KMT2ATHRBPPARGTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6011007-A | ZN2+ COMPLEX. | NOVO NORDISK A/S (DK) | 2000-01-04 | — | — | US | claimed |
| US-H810-H | MORPHINE AGONIST | Wilkinson, Samuel (GB) | 1990-08-07 | — | — | US | claimed |
| EP-0126344-A2 | Tripeptide esters of therapeutic agents | ABBOTT LABORATORIES (US) | 1984-11-28 | — | — | EP | claimed |
| CN-108834411-B | Polymeric biomaterials derived from phenolic monomers and their medical uses | 新泽西鲁特格斯州立大学 | 2022-01-25 | — | — | CN | disclosed |
| US-20060030518-A1 | Acylated insulin | SCIAPS, INC. | 2006-02-09 | — | — | US | disclosed |
| US-6869930-B1 | Acylated insulin | NOVO NORDISK A/S (DK) | 2005-03-22 | — | — | US | disclosed |
| EP-1379874-A1 | PHYCOERYTHRIN LABELED THYRONINE ANALOGUES AND ASSAYS USING THE LABELED ANALOGUES | BIO-RAD LABORATORIES, INC. (US) | 2004-01-14 | — | — | EP | disclosed |
| WO-2002073202-A1 | PHYCOERYTHRIN LABELED THYRONINE ANALOGUES AND ASSAYS USING THE LABELED ANALOGUES | BIO-RAD LABORATORIES, INC. (US) | 2002-09-19 | — | — | WO | disclosed |
| US-6423549-B1 | COMPETITIVE BINDING; IMMUNOASSAY; FLUORESCENT; MEDICAL DIAGNOSIS | BIO-RAD LABORATORIES, INC. | 2002-07-23 | — | — | US | disclosed |
| US-6001824-A | Butyryl-tyrosinyl spermine, analogs thereof and methods of preparing and using same | THE TRUSTEES OF COLUMBIA UNIVERSITY (US) | 1999-12-14 | — | — | US | disclosed |
| US-5770625-A | GLUTAMATE RECEPTOR BINDING INHIBITORS; INSECTICIDES; NERVOUS SYSTEM DISORDERS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 1998-06-23 | — | — | US | disclosed |
| WO-1996022962-A9 | BUTYRYL-TYROSINYL SPERMINE, ANALOGS THEREOF AND METHODS OF PREPARING AND USING SAME | — | 1996-10-03 | — | — | WO | disclosed |
| US-H810-H | MORPHINE AGONIST | Wilkinson, Samuel (GB) | 1990-08-07 | — | — | US | disclosed |
| EP-0126344-A2 | Tripeptide esters of therapeutic agents | ABBOTT LABORATORIES (US) | 1984-11-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060030518-A1 | Acylated insulin | INSR, BCAT1, SLC1A5 | SIRT5 3828/4885MEN1 1520/4885KMT2A 2109/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.