Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Ethylenediamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.62 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.50 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.49 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.49 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.49 |
| ▸ | IAPP | P10997 | 4/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | CASP6 | P55212 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8791 | 0.92 | AKR1B1 (0.72) | AKR1B1DUSP3PTPN5PTPN11CTDSP1 | |
| SCHEMBL29829095 | 0.92 | AKR1B1 (0.72) | AKR1B1DUSP3PTPN5PTPN11CTDSP1 | |
| Ethylenediamine SCHEMBL513767 | 0.86 | AKR1B1 (0.83) | AKR1B1DUSP3PTPN5PTPN11CTDSP1 | |
| Ethylenediamine SCHEMBL3489186 | 0.86 | AKR1B1 (0.83) | AKR1B1DUSP3PTPN5PTPN11CTDSP1 | |
| Ethylenediamine SCHEMBL28145957 | 0.85 | AKR1B1 (0.80) | AKR1B1DUSP3PTPN5PTPN11CTDSP1 | |
| SCHEMBL7937087 | 0.82 | AKR1B1 (0.67) | AKR1B1HMGB1DUSP3PTPN5PTPN11 | |
| Putrescine SCHEMBL9393794 | 0.79 | AKR1B1 (0.77) | AKR1B1DUSP3PTPN5PTPN11CTDSP1 | |
| SCHEMBL11029713 | 0.79 | GAA (0.53) | AKR1B1HMGB1IAPPTAAR1TDP1 | |
| SCHEMBL28717700 | 0.78 | IAPP (0.56) | AKR1B1HMGB1IAPPTAAR1TDP1 | |
| SCHEMBL29531687 | 0.78 | TAAR1 (0.68) | HMGB1IAPPTAAR1TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3113803-B1 | HYGIENE ARTICLE COMPRISING AN EFFECTIVE ODOUR CONTROL SYSTEM | ONTEX BVBA (BE) | 2019-02-13 | — | — | EP | claimed |
| US-20170216481-A1 | HYGIENE ARTICLE COMPRISING AN EFFECTIVE ODOUR CONTROL SYSTEM | ONTEX BV (BE) | 2017-08-03 | — | — | US | claimed |
| EP-3113803-A1 | HYGIENE ARTICLE COMPRISING AN EFFECTIVE ODOUR CONTROL SYSTEM | Ontex BVBA (BE) | 2017-01-11 | — | — | EP | claimed |
| WO-2015132267-A1 | HYGIENE ARTICLE COMPRISING AN EFFECTIVE ODOUR CONTROL SYSTEM | ONTEX BVBA (BE) | 2015-09-11 | — | — | WO | claimed |
| EP-2915547-A1 | Hygiene article comprising an effective odour control system | Ontex BVBA (BE) | 2015-09-09 | — | — | EP | claimed |
| EP-3753856-B1 | CHILDPROOF PACKAGE UNIT | DALLI WERKE GMBH & CO KG (DE) | 2023-10-11 | — | — | EP | disclosed |
| EP-3892707-A1 | LIQUID DETERGENT COMPOSITION, KIT AND DOSING SYSTEM | Dalli-Werke GmbH & Co. KG (DE) | 2021-10-13 | — | — | EP | disclosed |
| EP-3053997-B2 | Cleaning composition comprising a bleach catalyst and carboxymethylcellulose | DALLI WERKE GMBH & CO KG (DE) | 2021-01-13 | — | — | EP | disclosed |
| EP-3754003-A1 | DETERGENT PACKAGE UNIT WITH A HANDLE | Dalli-Werke GmbH & Co. KG (DE) | 2020-12-23 | — | — | EP | disclosed |
| EP-3753856-A1 | CHILDPROOF PACKAGE UNIT | Dalli-Werke GmbH & Co. KG (DE) | 2020-12-23 | — | — | EP | disclosed |
| EP-3190168-B1 | COATED BLEACH CATALYST | DALLI WERKE GMBH & CO KG (DE) | 2019-04-10 | — | — | EP | disclosed |
| EP-3113803-B1 | HYGIENE ARTICLE COMPRISING AN EFFECTIVE ODOUR CONTROL SYSTEM | ONTEX BVBA (BE) | 2019-02-13 | — | — | EP | disclosed |
| WO-2016005261-A1 | ENZYME - BLEACH CATALYST COGRANULATE SUITABLE FOR DETERGENT COMPOSITIONS | DALLI-WERKE GMBH & CO. KG (DE) | 2016-01-14 | — | — | WO | disclosed |
| EP-2966161-A1 | Enzyme-bleach catalyst cogranulate suitable for detergent compositions | Dalli-Werke GmbH & Co. KG (DE) | 2016-01-13 | — | — | EP | disclosed |
| WO-2015132267-A1 | HYGIENE ARTICLE COMPRISING AN EFFECTIVE ODOUR CONTROL SYSTEM | ONTEX BVBA (BE) | 2015-09-11 | — | — | WO | disclosed |
| EP-2915547-A1 | Hygiene article comprising an effective odour control system | Ontex BVBA (BE) | 2015-09-09 | — | — | EP | disclosed |
| US-20060051362-A1 | Antigens for actinobacillus pleuropneumoniae and methods thereof | JACQUES MARIO | 2006-03-09 | — | — | US | disclosed |
| EP-1458751-A2 | ANTIGENS FOR ACTINOBACILLUS PLEUROPNEUMONIAE AND METHODS THEREOF | UNIVERSITE DE MONTREAL (CA) | 2004-09-22 | — | — | EP | disclosed |
| WO-2003051913-A2 | ANTIGENS FOR ACTINOBACILLUS PLEUROPNEUMONIAE AND METHODS THEREOF | Université de Montréal (CA) | 2003-06-26 | — | — | WO | disclosed |
| US-4540667-A | Fluorescent siderophore genes | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1985-09-10 | — | — | US | disclosed |