Triphosphate

SCHEMBL6046309

Cc1cn([C@H]2C[C@H](O)[C@@H](CS)O2)c(=O)[nH]c1=O.O=P(O)(O)OP(=O)(O)OP(=O)(O)O

nearest known ligand 0.68

Predicted protein targets (top 6)

	gene	UniProt	supporting neighbours	confidence
▸	POLB	P06746	2/20	0.68

▸	POLA1	P09884	1/20	0.61

▸	POLD1	P28340	1/20	0.61

▸	TK1	P04183	5/20	0.57

▸	TYMS	P04818	1/20	0.56

▸	DTYMK	P23919	2/20	0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Doxribtimine SCHEMBL23421401	0.91	POLB (0.69)	POLBPOLA1POLD1TK1TYMS
Doxribtimine SCHEMBL1233441	0.91	POLB (0.69)	POLBPOLA1POLD1TK1TYMS
SCHEMBL8654924	0.90	TK1 (0.65)	POLBTK1
SCHEMBL778860	0.90	TK1 (0.65)	POLBTK1
Thymidine Monophosphate SCHEMBL28101717	0.89	POLB (0.79)	POLBPOLA1POLD1TK1TYMS
Deoxythymidine_Triphosphate SCHEMBL18785124	0.88	POLB (0.78)	POLBPOLA1POLD1TK1TYMS
Deoxythymidine_Triphosphate SCHEMBL14279191	0.88	POLB (0.78)	POLBPOLA1POLD1TK1TYMS
Deoxythymidine_Triphosphate SCHEMBL21275938	0.88	POLB (0.78)	POLBPOLA1POLD1TK1TYMS
SCHEMBL21682516	0.88	POLB (0.78)	POLBPOLA1POLD1TK1TYMS
Deoxythymidine_Triphosphate SCHEMBL11055949	0.88	POLB (0.78)	POLBPOLA1POLD1TK1TYMS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20060205040-A1	Compositions for use in identification of adventitious viruses	IBIS BIOSCIENCES, INC.	2006-09-14	—	—	US	disclosed