SCHEMBL6047002

SCHEMBL6047002

Cc1cn([C@H]2CC(OC(=O)Oc3ccc([N+](=O)[O-])cc3)[C@@H](CO)O2)c(=O)[nH]c1=O

nearest known ligand 0.62

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
RNASE1 P07998 1/20 0.62
TK1 P04183 2/20 0.49
TYMS P04818 1/20 0.48
TK2 O00142 1/20 0.48
LMNA P02545 2/20 0.48
TSHR P16473 2/20 0.48
ALB P02768 1/20 0.48
PKM P14618 1/20 0.48
BLM P54132 1/20 0.48
PMP22 Q01453 1/20 0.48
CYP2D6 P10635 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6046999 1.00 RNASE1 (0.62) RNASE1TK1TYMSTK2LMNA
SCHEMBL14378872 0.93 RNASE1 (0.53) RNASE1TK1TYMSTK2
SCHEMBL13681649 0.88 RNASE1 (0.66) RNASE1TK1TK2ALBPKM
SCHEMBL14094316 0.88 RNASE1 (0.66) RNASE1TK1TK2ALBPKM
SCHEMBL31289411 0.87 RNASE1 (0.50) RNASE1TK1TYMS
SCHEMBL8424441 0.83 RNASE1 (0.53) RNASE1TK1TYMSLMNATSHR
SCHEMBL6046985 0.83 RNASE1 (0.49) RNASE1TK1TYMSTK2
SCHEMBL6046988 0.83 RNASE1 (0.49) RNASE1TK1TYMSTK2
SCHEMBL6047004 0.83 TYMS (0.58) TYMS
SCHEMBL6047006 0.83 TYMS (0.58) TYMS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060154256-A1 Method for covalently attaching nucleosides and/or nucleotides on surfaces and method for determining coupling yields in the synthesis of nucleotides CHEMOGENIX GMBH (DE) 2006-07-13 US disclosed
US-20040203036-A1 Multimer polynucleotide synthesis CHEMOGENIX GMBH (DE) 2004-10-14 US disclosed
EP-1438322-A2 METHOD FOR COVALENTLY ATTACHING NUCLEOSIDES AND/OR NUCLEOTIDES ON SURFACES AND METHOD FOR DETERMINING COUPLING YIELDS IN THE SYNTHESIS OF NUCLEOTIDES Chemogenix GmbH (DE) 2004-07-21 EP disclosed
EP-1409505-A1 MULTIMER POLYNUCLEOTIDE SYNTHESIS Chemogenix GmbH (DE) 2004-04-21 EP disclosed
WO-2003035664-A2 METHOD FOR COVALENTLY ATTACHING NUCLEOSIDES AND/OR NUCLEOTIDES ON SURFACES AND METHOD FOR DETERMINING COUPLING YIELDS IN THE SYNTHESIS OF NUCLEOTIDES CHEMOGENIX GMBH (DE) 2003-05-01 WO disclosed
WO-2003006476-A1 MULTIMER POLYNUCLEOTIDE SYNTHESIS CHEMOGENIX GMBH (DE) 2003-01-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040203036-A1 Multimer polynucleotide synthesis NT5C3B, PCNA, POLL RNASE1 205/4885TK1 176/4885TYMS 329/4885
US-20060154256-A1 Method for covalently attaching nucleosides and/or nucleotides on surfaces and method for determining coupling yields in the synthesis of nucleotides NUDT1, PNP, NME2 RNASE1 1368/4885TK1 71/4885TYMS 80/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.