Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASE1 | P07998 | 1/20 | 0.53 |
| ▸ | TYMS | P04818 | 1/20 | 0.53 |
| ▸ | TK1 | P04183 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | ALB | P02768 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29652182 | 0.88 | RNASE1 (0.56) | RNASE1TYMSTK1LMNATSHR | |
| Doxribtimine SCHEMBL20797965 | 0.87 | TYMS (0.63) | TYMSTK1LMNA | |
| SCHEMBL548542 | 0.85 | TYMS (0.54) | RNASE1TYMSTK1 | |
| SCHEMBL30761816 | 0.84 | RNASE1 (0.52) | RNASE1TYMSTK1LMNATSHR | |
| SCHEMBL3063249 | 0.84 | TYMS (0.68) | TYMSTK1 | |
| SCHEMBL8428624 | 0.84 | TYMS (0.68) | TYMSTK1 | |
| SCHEMBL6046999 | 0.83 | RNASE1 (0.62) | RNASE1TYMSTK1LMNATSHR | |
| SCHEMBL6047002 | 0.83 | RNASE1 (0.62) | RNASE1TYMSTK1LMNATSHR | |
| Ammonia Solution, Strong SCHEMBL8170309 | 0.83 | TYMS (0.67) | TYMSTK1 | |
| SCHEMBL19223589 | 0.82 | TK1 (0.63) | RNASE1TK1LMNATSHRALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962291-A | MONOCLONAL ANTIBODY CAPABLE OF HYDROLYZING A SUBSTRATE; HAS TWO BINDING SITES: ONE FOR FREE METAL ION, ONE FOR SUBSTRATE | THE REGENTS OF THE UNIVERSITY OF COLORADO (US) | 1999-10-05 | — | — | US | disclosed |
| EP-0061762-B1 | NUCLEOTIDE-BASED SUBSTRATES | Baker Instruments Corporation (US) | 1988-03-02 | — | — | EP | disclosed |