Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.34 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6047598 | 0.83 | HTR2C (0.39) | CHRNB4CHRNA3RAB9ANPC1TSHR | |
| SCHEMBL6047612 | 0.79 | MAOB (0.40) | L3MBTL1ACHERAB9AALDH1A1MEN1 | |
| SCHEMBL4808757 | 0.71 | ESR2 (0.39) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5887199 | 0.70 | KMT2A (0.35) | L3MBTL1ACHERAB9AALDH1A1MEN1 | |
| SCHEMBL5887404 | 0.70 | L3MBTL1 (0.40) | L3MBTL1ACHENISCHCHRNB4CHRNA3 | |
| SCHEMBL5887311 | 0.69 | KMT2A (0.36) | L3MBTL1ACHENISCHCHRNB4CHRNA3 | |
| SCHEMBL5781630 | 0.68 | NUDT1 (0.35) | CHRNB4CHRNA3HTR7 | |
| SCHEMBL5887353 | 0.67 | MEN1 (0.35) | L3MBTL1ACHENISCHRAB9AMEN1 | |
| SCHEMBL31471473 | 0.66 | ACHE (0.69) | ACHENISCHCHRNB4CHRNA3RAB9A | |
| SCHEMBL29373699 | 0.66 | ACHE (0.69) | ACHENISCHCHRNB4CHRNA3RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2006501194-A | — | — | 2006-01-12 | — | — | JP | claimed |
| EP-1525190-A1 | CCK-1 RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2005-04-27 | — | — | EP | claimed |
| WO-2004007463-A1 | CCK-1 RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2004-01-22 | — | — | WO | claimed |