Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.35 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.34 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5887672 | 0.90 | ESR2 (0.40) | PGRPARP10PARP11ESR2 | |
| SCHEMBL5887587 | 0.87 | ESR1 (0.33) | L3MBTL1MEN1KMT2AHPGDKDM4E | |
| SCHEMBL4802233 | 0.85 | ESR1 (0.40) | HPGDKDM4EALDH1A1MAPTESR1 | |
| SCHEMBL5887570 | 0.85 | ALKBH3 (0.44) | L3MBTL1CLK4HPGDKDM4EALDH1A1 | |
| SCHEMBL6047653 | 0.81 | HSD11B1 (0.37) | MAPT | |
| SCHEMBL6047589 | 0.75 | PTGS1 (0.35) | L3MBTL1MEN1KMT2APGR | |
| SCHEMBL6047649 | 0.70 | L3MBTL1 (0.38) | L3MBTL1MEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL23003863 | 0.68 | ACHE (0.55) | L3MBTL1MEN1KMT2AFYNCLK4 | |
| SCHEMBL5545442 | 0.68 | ACHE (0.55) | L3MBTL1MEN1KMT2AFYNCLK4 | |
| SCHEMBL29929976 | 0.68 | ACHE (0.55) | L3MBTL1MEN1KMT2AFYNCLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7037931-B2 | Corticotropin releasing factor moderator; analgesics; drug abruse, drug dependency; schizophrenia | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-05-02 | — | — | US | claimed |