Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | VCP | P55072 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6047855 | 0.81 | HTR7 (0.44) | RAB9ANPC1SMN1; SMN2PTGS2MAPT | |
| SCHEMBL12682421 | 0.75 | MAPT (0.55) | RAB9ANPC1SMN1; SMN2HPGDMAPT | |
| SCHEMBL7970512 | 0.73 | RAB9A (0.53) | RAB9ANPC1SMN1; SMN2HPGDPTGS2 | |
| SCHEMBL6047843 | 0.72 | ALDH1A1 (0.47) | RAB9ANPC1HPGDPTGS2MAPT | |
| SCHEMBL6309234 | 0.71 | ALDH1A1 (0.57) | RAB9ANPC1SMN1; SMN2HPGDMAPT | |
| SCHEMBL27777515 | 0.71 | TDP1 (0.43) | SMN1; SMN2PTGS2MAPTMEN1KMT2A | |
| SCHEMBL27969541 | 0.69 | PTGS2 (0.64) | RAB9ANPC1SMN1; SMN2PTGS2MAPT | |
| SCHEMBL21808049 | 0.69 | TDP1 (0.42) | SMN1; SMN2PTGS2MAPTMEN1KMT2A | |
| SCHEMBL12937568 | 0.69 | HPGD (0.49) | RAB9ANPC1SMN1; SMN2HPGDMAPT | |
| SCHEMBL6889537 | 0.68 | PKM (0.43) | RAB9ASMN1; SMN2PTGS2MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006117556-A2 | MATERIALS AND METHODS FOR THE PHOTODIRECTED SYNTHESIS OF OLIGONUCLEOTIDE ARRAYS | THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) | 2006-11-09 | — | — | WO | claimed |
| WO-2006117556-A2 | MATERIALS AND METHODS FOR THE PHOTODIRECTED SYNTHESIS OF OLIGONUCLEOTIDE ARRAYS | THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) | 2006-11-09 | — | — | WO | disclosed |