Malonic Acid

Malonic Acid

SCHEMBL6048075

CN(C)CCCNCc1ccccc1.O=C(O)CC(=O)O

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CCR6 P51684 1/20 0.55
PAX8 Q06710 1/20 0.55
MAOA P21397 1/20 0.53
SIGMAR1 Q99720 4/20 0.52
TMEM97 Q5BJF2 1/20 0.52
CHRM2 P08172 1/20 0.51
HDAC3 O15379 2/20 0.51
HDAC1 Q13547 2/20 0.51
HDAC2 Q92769 2/20 0.51
HDAC8 Q9BY41 2/20 0.51
NCOR2 Q9Y618 2/20 0.51
KDM4E B2RXH2 2/20 0.51
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
TDP1 Q9NUW8 1/20 0.48
PKM P14618 1/20 0.47
ALOX15 P16050 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1443953 0.90 MAOA (0.64) CCR6PAX8MAOASIGMAR1TMEM97
Hydrochloric Acid SCHEMBL21493579 0.89 MAOA (0.62) CCR6PAX8MAOASIGMAR1TMEM97
SCHEMBL16151778 0.87 CHRM2 (0.63) CCR6PAX8MAOASIGMAR1TMEM97
Hydrochloric Acid SCHEMBL29778342 0.85 CHRM2 (0.61) CCR6PAX8MAOASIGMAR1TMEM97
SCHEMBL2478156 0.81 LTA4H (0.55) CCR6PAX8SIGMAR1TMEM97HDAC1
SCHEMBL4398241 0.80 CCR6 (0.60) CCR6PAX8SIGMAR1TMEM97KDM4E
SCHEMBL30090684 0.80 SIGMAR1 (0.69) CCR6PAX8MAOASIGMAR1TMEM97
SCHEMBL133622 0.79 MEN1 (0.64) MAOASIGMAR1TMEM97CHRM2HDAC1
SCHEMBL5915547 0.78 ALDH1A1 (0.47) CCR6PAX8SIGMAR1TMEM97HDAC1
Ammonia Solution, Strong SCHEMBL16268586 0.78 MEN1 (0.61) MAOASIGMAR1TMEM97CHRM2HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7026428-B2 Blocked polyisocyanates BAYER AKTIENGESELLSCHAFT (DE) 2006-04-11 US disclosed
US-20030232953-A1 Blocked polyisocyanates BAYER AKTIENGESELLSCHAFT (DE) 2003-12-18 US disclosed