Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 8/20 | 0.41 |
| ▸ | LIPE | Q05469 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.37 |
| ▸ | STS | P08842 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7170392 | 0.89 | EPHX2 (0.42) | EPHX2LIPEKMT2APTPN1MAPT | |
| SCHEMBL6049200 | 0.82 | KIF11 (0.45) | EPHX2LIPEKMT2AMAPTBRD4 | |
| SCHEMBL30596308 | 0.75 | SCD5 (0.54) | EPHX2LIPENPC1GPR119SCD5 | |
| Hydrochloric Acid SCHEMBL6049206 | 0.73 | PTPN1 (0.43) | EPHX2MEN1KMT2APTPN1BRD4 | |
| SCHEMBL6049181 | 0.73 | SLC6A4 (0.52) | EPHX2MAPT | |
| SCHEMBL2645354 | 0.73 | GPR119 (0.48) | MEN1KMT2AGPR119 | |
| SCHEMBL6049210 | 0.71 | SCD5 (0.38) | EPHX2BRD4SCD5 | |
| SCHEMBL6049230 | 0.71 | PTPN1 (0.38) | EPHX2PTPN1MAPTBRD4 | |
| SCHEMBL2645042 | 0.70 | GCK (0.47) | MEN1KMT2AGPR119 | |
| SCHEMBL28660312 | 0.68 | HSP90AA1 (0.47) | NPC1SMN1; SMN2SCD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1184372-B1 | Phenoxyphenylheterocycle derivatives as selective serotonin reuptake inhibitors (SSRIs) | PFIZER LTD (GB) | 2006-04-26 | — | — | EP | disclosed |