Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.52 |
| ▸ | FPR2 | P25090 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 2/20 | 0.40 |
| ▸ | BRAF | P15056 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | NPY2R | P49146 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | MMP14 | P50281 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6049200 | 0.91 | KIF11 (0.45) | SLC6A4SLC6A2SLC6A3FPR2KIF11 | |
| SCHEMBL7170392 | 0.81 | EPHX2 (0.42) | HRH3MAPTEPHX2MMP3MMP9 | |
| SCHEMBL6049259 | 0.78 | RAB9A (0.44) | MAPT | |
| SCHEMBL6049260 | 0.78 | RAB9A (0.44) | MAPT | |
| SCHEMBL6049210 | 0.73 | SCD5 (0.38) | SLC6A4SLC6A2SLC6A3HRH3EPHX2 | |
| SCHEMBL6049231 | 0.73 | EPHX2 (0.41) | MAPTEPHX2 | |
| SCHEMBL6049177 | 0.70 | HSP90AA1 (0.41) | MAPTHSD11B1MMP2MMP3MMP9 | |
| SCHEMBL3111013 | 0.70 | KIF11 (0.73) | SLC6A4SLC6A2SLC6A3KIF11MMP2 | |
| SCHEMBL17142310 | 0.69 | RIPK1 (0.51) | HRH3DPP4 | |
| SCHEMBL6049191 | 0.69 | GCK (0.43) | HRH3MAPTEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1184372-B1 | Phenoxyphenylheterocycle derivatives as selective serotonin reuptake inhibitors (SSRIs) | PFIZER LTD (GB) | 2006-04-26 | — | — | EP | disclosed |
| EP-1184372-A1 | Phenoxyphenylheterocycle derivatives as selective serotonin reuptake inhibitors (SSRIs) | Pfizer Limited (GB) | 2002-03-06 | — | — | EP | disclosed |