Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 10/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | LIPE | Q05469 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | MMP7 | P09237 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | MMP14 | P50281 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6049200 | 0.91 | KIF11 (0.45) | EPHX2LIPEMAPTKMT2ABRD4 | |
| SCHEMBL6049231 | 0.89 | EPHX2 (0.41) | EPHX2PTPN1LIPETP53MAPT | |
| SCHEMBL6049181 | 0.81 | SLC6A4 (0.52) | EPHX2MMP3MMP9MMP8MMP13 | |
| SCHEMBL6049210 | 0.79 | SCD5 (0.38) | EPHX2MMP1MMP3MMP7MMP9 | |
| SCHEMBL6049191 | 0.78 | GCK (0.43) | EPHX2TP53MAPTSMN1; SMN2KMT2A | |
| SCHEMBL6049192 | 0.78 | GCK (0.43) | EPHX2TP53MAPTSMN1; SMN2KMT2A | |
| Hydrochloric Acid SCHEMBL6049206 | 0.76 | PTPN1 (0.43) | EPHX2PTPN1KMT2ABRD4 | |
| SCHEMBL6049230 | 0.73 | PTPN1 (0.38) | EPHX2PTPN1MMP1MMP3MMP9 | |
| SCHEMBL6049259 | 0.69 | RAB9A (0.44) | MAPTSMN1; SMN2KMT2A | |
| SCHEMBL6049260 | 0.69 | RAB9A (0.44) | MAPTSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6630504-B2 | Activity as selective serotonin re- uptake inhibitors (SSRIs); for therapy and prophylaxis of depression, attention deficit hyperactivity disorder, obsessive-compulsive disorder, post-traumatic stress disorder, sexual dysfunction | PFIZER INC. | 2003-10-07 | — | — | US | disclosed |
| US-20020183303-A1 | Phenoxyphenylheterocyclyl derivatives as SSRIs | PFIZER INC. | 2002-12-05 | — | — | US | disclosed |
| EP-1184372-A1 | Phenoxyphenylheterocycle derivatives as selective serotonin reuptake inhibitors (SSRIs) | Pfizer Limited (GB) | 2002-03-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020183303-A1 | Phenoxyphenylheterocyclyl derivatives as SSRIs | CRHR1, NR3C1, HTR6 | EPHX2 530/4885PTPN1 2516/4885LIPE 3923/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.