SCHEMBL6049296

SCHEMBL6049296

COCOc1ccc(CCC(CCc2ccccc2)OC(=S)NCCc2ccccc2)cc1OCOC

nearest known ligand 0.70

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.46
MEN1 O00255 1/20 0.46
PPARG P37231 2/20 0.45
PPARA Q07869 2/20 0.45
MAPT P10636 1/20 0.43
PLAAT3 P53816 1/20 0.42
PLAAT5 Q96KN8 1/20 0.42
PLAAT2 Q9NWW9 1/20 0.42
PLAAT4 Q9UL19 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6049228 0.89 PPARG (0.46) PPARGPPARAPLAAT3PLAAT5PLAAT2
SCHEMBL6049411 0.83
SCHEMBL6049279 0.79
SCHEMBL6049275 0.78 GAA (0.53) KMT2AMEN1MAPT
SCHEMBL6049308 0.78 MEN1 (0.46) KMT2AMEN1MAPT
SCHEMBL6049295 0.75 LMNA (0.49) KMT2AMEN1MAPT
SCHEMBL6049319 0.75 KMT2A (0.47) KMT2AMEN1MAPTPLAAT3PLAAT5
SCHEMBL6049253 0.74 PPARA (0.48) PPARGPPARAMAPT
SCHEMBL10602701 0.72 MTNR1A (0.60) KMT2AMEN1MAPTPLAAT3PLAAT5
SCHEMBL6049301 0.68 NPC1 (0.48) PPARGPPARAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060264480-A1 Novel thiocarbamic acid derivatives and the pharmaceutical compositions containing the same SUH YOUNG G 2006-11-23 US disclosed
US-20030203944-A1 Novel thiocarbamic acid derivatives and the pharmaceutical compositions containing the same PACIFIC CORPORATION (KR) 2003-10-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060264480-A1 Novel thiocarbamic acid derivatives and the pharmaceutical compositions containing the same TRPV1, TRPA1, TRPV5 KMT2A 4450/4885MEN1 3797/4885PPARG 1142/4885
US-20030203944-A1 Novel thiocarbamic acid derivatives and the pharmaceutical compositions containing the same TRPV1, TRPA1, TRPV5 KMT2A 4450/4885MEN1 3797/4885PPARG 1142/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.