SCHEMBL6049412

SCHEMBL6049412

CCOC(=O)c1ccc(Br)cc1C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.59
TSHR P16473 1/20 0.55
GABRA1 P14867 1/20 0.51
GABRB1 P18505 1/20 0.51
GABRA3 P34903 1/20 0.51
GABRB2 P47870 1/20 0.51
CA12 O43570 2/20 0.50
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
CA7 P43166 2/20 0.50
CA9 Q16790 2/20 0.50
CA14 Q9ULX7 2/20 0.50
LMNA P02545 2/20 0.49
MYC P01106 1/20 0.47
NR4A1 P22736 1/20 0.47
KDM4E B2RXH2 1/20 0.47
GLA P06280 1/20 0.47
SORT1 Q99523 6/20 0.47
PDE3B Q13370 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21857616 0.93 ALDH1A1 (0.56) ALDH1A1SMN1; SMN2TSHRGABRA1GABRB1
SCHEMBL234030 0.91 TSHR (0.60) ALDH1A1SMN1; SMN2TSHRGABRA1GABRB1
SCHEMBL27444525 0.87 TSHR (0.55) ALDH1A1SMN1; SMN2TSHRGABRA1GABRB1
SCHEMBL22552343 0.85 TSHR (0.53) ALDH1A1SMN1; SMN2TSHRGABRA1GABRB1
SCHEMBL28989946 0.85 TSHR (0.53) ALDH1A1SMN1; SMN2TSHRGABRA1GABRB1
SCHEMBL28877583 0.84 ATM (0.60) ALDH1A1SMN1; SMN2TSHRLMNAATM
SCHEMBL16108187 0.83 TSHR (0.56) ALDH1A1SMN1; SMN2TSHRGABRA1GABRB1
SCHEMBL8158480 0.83 CA12 (0.57) ALDH1A1SMN1; SMN2TSHRGABRA1GABRB1
SCHEMBL289045 0.83 ALDH1A1 (0.55) ALDH1A1SMN1; SMN2TSHRGABRA1GABRB1
SCHEMBL288615 0.83 ALDH1A1 (0.55) ALDH1A1SMN1; SMN2TSHRGABRA1GABRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120081801-A Tetracarboxylic acid organic ligand based on benzothiadiazole functional group for preparing metal organic framework, and preparation method and application thereof 江西理工大学 2025-06-03 CN claimed
CN-118082333-A Multilayer antibacterial SPC board and preparation process thereof 福建福晟新材料科技有限公司 2024-05-28 CN claimed
CN-120081801-A Tetracarboxylic acid organic ligand based on benzothiadiazole functional group for preparing metal organic framework, and preparation method and application thereof 江西理工大学 2025-06-03 CN disclosed
WO-2025110797-A1 BATTERY MODULE HAVING FIRE-EXTINGUISHING LAYER AND BATTERY FIRE BLOCKING STICK 주식회사 네패스야하드 2025-05-30 WO disclosed
WO-2025023562-A1 SECONDARY BATTERY CELL HAVING FIRE EXTINGUISHING LAYER FORMED THEREIN 주식회사 네패스야하드 2025-01-30 WO disclosed
CN-118082333-A Multilayer antibacterial SPC board and preparation process thereof 福建福晟新材料科技有限公司 2024-05-28 CN disclosed
WO-2024029874-A1 BATTERY MODULE AND BATTERY PACK WITH FIRE EXTINGUISHING FUNCTION 주식회사 네패스야하드 2024-02-08 WO disclosed
US-20230047816-A1 PFKFB3 INHIBITORS AND THEIR USES GERO PTE. LTD. (SG) 2023-02-16 US disclosed
US-20230047816-A1 PFKFB3 INHIBITORS AND THEIR USES GERO PTE. LTD. (SG) 2023-02-16 US disclosed
CN-113396145-A PFKFB3 inhibitors and uses thereof 盖罗发现有限责任公司 2021-09-14 CN disclosed
WO-2020080979-A1 PFKFB3 INHIBITORS AND THEIR USES GERO DISCOVERY LIMITED LIABILITY COMPANY (RU) 2020-04-23 WO disclosed
US-20060264480-A1 Novel thiocarbamic acid derivatives and the pharmaceutical compositions containing the same SUH YOUNG G 2006-11-23 US disclosed
CN-1214008-C Therapeutic biaryl derivatives GLAXO GROUP LTD (GB) 2005-08-10 CN disclosed
EP-1311477-A4 NOVEL THIOCARBAMIC ACID DERIVATIVES AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME PACIFIC CORP (KR) 2005-01-12 EP disclosed
US-20030203944-A1 Novel thiocarbamic acid derivatives and the pharmaceutical compositions containing the same PACIFIC CORPORATION (KR) 2003-10-30 US disclosed
EP-1311477-A1 NOVEL THIOCARBAMIC ACID DERIVATIVES AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME PACIFIC CORPORATION (KR) 2003-05-21 EP disclosed
WO-2002016317-A1 NOVEL THIOCARBAMIC ACID DERIVATIVES AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME PACIFIC CORPORATION (KR) 2002-02-28 WO disclosed
CN-1312800-A Therapeutic biaryl derivatives GLAXO GROUP LTD (GB) 2001-09-12 CN disclosed
CN-1065861-C Phenyl substituted alkenocarboxylic guanidine, preparation method, application as medicine or diagnostic agent adn medicine containing it HOECHST AG (DE) 2001-05-16 CN disclosed
CN-1174833-A Phenyl substituted alkenocarboxylic guanidine, preparation method, application as medicine or diagnostic agent adn medicine containing it HOECHST AG (DE) 1998-03-04 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060264480-A1 Novel thiocarbamic acid derivatives and the pharmaceutical compositions containing the same TRPV1, TRPA1, TRPV5 ALDH1A1 1887/4885SMN1; SMN2 1555/4885TSHR 864/4885
US-20230047816-A1 PFKFB3 INHIBITORS AND THEIR USES PFKFB3, PFKFB4, PFKFB1 ALDH1A1 1943/4885SMN1; SMN2 1192/4885TSHR 4576/4885
US-20030203944-A1 Novel thiocarbamic acid derivatives and the pharmaceutical compositions containing the same TRPV1, TRPA1, TRPV5 ALDH1A1 1887/4885SMN1; SMN2 1555/4885TSHR 864/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.