SCHEMBL6050558

SCHEMBL6050558

O=c1c(=O)c(=O)c2ccccc2c1=O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.48
KDM4E B2RXH2 4/20 0.48
SMN1; SMN2 Q16637 3/20 0.48
MAPT P10636 3/20 0.48
GAA P10253 3/20 0.48
LMNA P02545 3/20 0.48
HSD17B10 Q99714 3/20 0.48
GLA P06280 2/20 0.48
HPGD P15428 2/20 0.48
HTT P42858 2/20 0.48
ATM Q13315 1/20 0.48
CYP3A4 P08684 1/20 0.48
PGAM1 P18669 1/20 0.48
MAOA P21397 1/20 0.48
CASP1 P29466 1/20 0.48
CASP7 P55210 1/20 0.48
S100A4 P26447 1/20 0.42
POLB P06746 2/20 0.42
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17987 1.00 ALDH1A1 (0.48) ALDH1A1KDM4ESMN1; SMN2MAPTGAA
SCHEMBL29362920 1.00 ALDH1A1 (0.48) ALDH1A1KDM4ESMN1; SMN2MAPTGAA
SCHEMBL4921603 0.96 ALDH1A1 (0.46) ALDH1A1KDM4ESMN1; SMN2MAPTGAA
SCHEMBL30139899 0.96 ALDH1A1 (0.46) ALDH1A1KDM4ESMN1; SMN2MAPTGAA
Water SCHEMBL1512563 0.96 ALDH1A1 (0.46) ALDH1A1KDM4ESMN1; SMN2MAPTGAA
SCHEMBL5536637 0.96 ALDH1A1 (0.46) ALDH1A1KDM4ESMN1; SMN2MAPTGAA
Water SCHEMBL592692 0.96 ALDH1A1 (0.46) ALDH1A1KDM4ESMN1; SMN2MAPTGAA
Water SCHEMBL29662270 0.96 ALDH1A1 (0.46) ALDH1A1KDM4ESMN1; SMN2MAPTGAA
SCHEMBL4930798 0.96 ALDH1A1 (0.46) ALDH1A1KDM4ESMN1; SMN2MAPTGAA
Water SCHEMBL28087086 0.96 ALDH1A1 (0.46) ALDH1A1KDM4ESMN1; SMN2MAPTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110628476-B Pretreatment method and purifying agent for refinery rich gas and desulfurization method for dry gas and/or liquefied gas 中国石油化工股份有限公司 2020-11-13 CN claimed
CN-110628476-A Pretreatment method and purifying agent for refinery rich gas and desulfurization method for dry gas and/or liquefied gas 中国石油化工股份有限公司 2019-12-31 CN claimed
US-9717699-B2 Sterilized compositions of cyanoacrylate monomers and naphthoquinone 2,3-oxides ADHEZION BIOMEDICAL, LLC (US) 2017-08-01 US claimed
US-20160331700-A1 Sterilized Compositions of Cyanoacrylate Monomers and Naphthoquinone 2,3-Oxides H.B. FULLER MEDICAL ADHESIVE TECHNOLOGIES, LLC. 2016-11-17 US claimed
US-20150283290-A1 STERILIZED COMPOSITIONS OF CYANOACRYLATE MONOMERS AND NAPHTHOQUINONE 2,3-OXIDES ADHEZION BIOMEDICAL, LLC (US) 2015-10-08 US claimed
EP-1525001-A1 CONJUGATES OF PORPHYRIN COMPOUNDS WITH CHEMOTHERAPEUTIC AGENTS Cellgate Inc. (US) 2005-04-27 EP claimed
US-20040192665-A1 Conjugates of porphyrin compounds with chemotherapeutic agents SLIL BIOMEDICAL CORPORATION 2004-09-30 US claimed
WO-2004012774-A1 CONJUGATES OF PORPHYRIN COMPOUNDS WITH CHEMOTHERAPEUTIC AGENTS CELLGATE, INC. (US) 2004-02-12 WO claimed
EP-0759040-B1 CARBONYL CONTAINING COMPOUNDS AND THEIR DERIVATIVES AS MULTI-FUNCTIONAL FUEL AND LUBE ADDITIVES EXXON RESEARCH ENGINEERING CO (US) 1999-01-27 EP claimed
CN-117062636-A Catheter securement compositions and methods 艾德合森生物医药有限责任公司 2023-11-14 CN disclosed
US-20230302144-A1 Porphyrin Compounds and Compositions Useful for Treating Cancer ONCOSELECT THERAPEUTICS, LLC (US) 2023-09-28 US disclosed
US-11590233-B2 Porphyrin compounds and compositions useful for treating cancer ONCOSELECT THERAPEUTICS, LLC (US) 2023-02-28 US disclosed
CN-109922834-B Porphyrin compounds and compositions for the treatment of cancer 良药治疗公司 2022-09-23 CN disclosed
US-20220218951-A1 CATHETER SECUREMENT COMPOSITIONS AND METHODS PROVIDING SIGNIFICANTLY STRONG SECUREMENT, WATER RESISTANT SEAL, EFFECTIVE HEMOSTATIS, AND ANTIBACTERIAL PROPERTIES AT AND AROUND VASCULAR ACCESS SITES H.B. FULLER MEDICAL ADHESIVE TECHNOLOGIES, LLC. 2022-07-14 US disclosed
EP-0759040-A1 CARBONYL CONTAINING COMPOUNDS AND THEIR DERIVATIVES AS MULTI-FUNCTIONAL FUEL AND LUBE ADDITIVES EXXON RESEARCH AND ENGINEERING COMPANY (US) 1997-02-26 EP disclosed
WO-1995031488-A1 CARBONYL CONTAINING COMPOUNDS AND THEIR DERIVATIVES AS MULTI-FUNCTIONAL FUEL AND LUBE ADDITIVES EXXON RESEARCH AND ENGINEERING COMPANY (US) 1995-11-23 WO disclosed
US-5314914-A Methods and compositions for combatting herpes viruses BIOMEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) 1994-05-24 US disclosed
US-5242946-A Treating herpes Viral infections BIO-MEGA, INC. (CA) 1993-09-07 US disclosed
US-4216078-A Hydrogenation of petroleum liquids using quinone catalysts EXXON RESEARCH & ENGINEERING CO. (US) 1980-08-05 US disclosed
US-4049537-A SLURRYING COAL, SOLVENT, AND A QUINONE, CONTACTING WITH HYDROGEN EXXON RESEARCH & ENGINEERING CO. (US) 1977-09-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040192665-A1 Conjugates of porphyrin compounds with chemotherapeutic agents PPOX, PPIF, HMBS ALDH1A1 1866/4885KDM4E 2831/4885SMN1; SMN2 1882/4885
US-20230302144-A1 Porphyrin Compounds and Compositions Useful for Treating Cancer KIT, HCCS, PPIF ALDH1A1 2847/4885KDM4E 2828/4885SMN1; SMN2 2987/4885
US-11590233-B2 Porphyrin compounds and compositions useful for treating cancer KIT, HCCS, PPIF ALDH1A1 2847/4885KDM4E 2828/4885SMN1; SMN2 2987/4885
US-20160331700-A1 Sterilized Compositions of Cyanoacrylate Monomers and Naphthoquinone 2,3-Oxides PROC, CCNK, MMS19 ALDH1A1 1806/4885KDM4E 1898/4885SMN1; SMN2 1847/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.