SCHEMBL6053

SCHEMBL6053

O=C(O)C1C2C=CC(C2)C1C(=O)NO

nearest known ligand 0.57

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.57
POLB P06746 4/20 0.55
CASP6 P55212 1/20 0.55
CTDSP1 Q9GZU7 1/20 0.55
TDP1 Q9NUW8 3/20 0.54
APEX1 P27695 1/20 0.52
NPSR1 Q6W5P4 1/20 0.51
TAAR1 Q96RJ0 1/20 0.51
HSD17B10 Q99714 1/20 0.51
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
GAA P10253 2/20 0.49
KDM4E B2RXH2 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14469601 0.84 POLB (0.70) ALDH1A1POLBCASP6CTDSP1TDP1
SCHEMBL381246 0.84 POLB (0.70) ALDH1A1POLBCASP6CTDSP1TDP1
SCHEMBL14577505 0.84 POLB (0.70) ALDH1A1POLBCASP6CTDSP1TDP1
SCHEMBL24062391 0.84 POLB (0.70) ALDH1A1POLBCASP6CTDSP1TDP1
SCHEMBL20346210 0.84 POLB (0.70) ALDH1A1POLBCASP6CTDSP1TDP1
SCHEMBL23287488 0.84 POLB (0.70) ALDH1A1POLBCASP6CTDSP1TDP1
SCHEMBL1462188 0.84 POLB (0.70) ALDH1A1POLBCASP6CTDSP1TDP1
SCHEMBL713506 0.84 POLB (0.70) ALDH1A1POLBCASP6CTDSP1TDP1
SCHEMBL59471 0.84 POLB (0.70) ALDH1A1POLBCASP6CTDSP1TDP1
SCHEMBL5641704 0.84 POLB (0.70) ALDH1A1POLBCASP6CTDSP1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 657 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250034290-A1 Functional Cyclic Olefin Polymer, Process for Obtaining the Same and Compositions Containing the Same EXXONMOBIL CHEMICAL PATENTS INC (US) 2025-01-30 US claimed
CN-115038703-B Preparation method of tofacitinib and intermediate product thereof 阿尔第实业有限公司 2024-08-06 CN claimed
EP-3450439-B1 METHOD FOR PRODUCING MONOMER FOR SINGLE-STRANDED NUCLEIC ACID MOLECULE SUMITOMO CHEMICAL CO (JP) 2021-01-20 EP claimed
US-10308672-B2 Method for producing monomer for single-stranded nucleic acid molecule SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2019-06-04 US claimed
US-20190100540-A1 METHOD FOR PRODUCING MONOMER FOR SINGLE-STRANDED NUCLEIC ACID MOLECULE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2019-04-04 US claimed
EP-2519100-B1 INTERMEDIATE COMPOUNDS AND PROCESSES FOR THE PREPARATION OF TAPENTADOL AND RELATED COMPOUNDS MAPI PHARMA LTD (IL) 2017-03-15 EP claimed
US-7288661-B2 Process for the synthesis of (2S,3aS,7aS)-1-[(S)-alanyl]-octahydro-1H-indole-2-carboxylic acid compounds and application in the synthesis of perindopril LES LABORATOIRES SERVIER (FR) 2007-10-30 US claimed
US-20070123581-A1 Process for the synthesis of (2s, 3as, 7as)-1-[(s)-alanyl]-octahydro-1h-indole-2-carboxylic acid compounds and application in the synthesis of perindopril LES LABORATOIRES SERVIER (FR) 2007-05-31 US claimed
US-20070093663-A1 Process for the synthesis of perindopril and pharmaceutically acceptable salts thereof. LES LABORATOIRES SERVIER (FR) 2007-04-26 US claimed
US-6602649-B2 Photolithography; using ultraviolet radiation HYNIX SEMICONDUCTOR INC (KR) 2003-08-05 US claimed
US-20020015912-A1 Photoresist monomers, polymers thereof and photoresist compositions containing the same HYNIX SEMICONDUCTOR INC. (KR) 2002-02-07 US claimed
US-5670647-A Method for recovering optically pure amino acid derivatives SHIMADZU CORPORATION (JP) 1997-09-23 US claimed
JP-59112945-A None JP disclosed
JP-59122465-A None JP disclosed
JP-55051045-A None JP disclosed
US-20260144900-A1 IN VIVO CROSSLINKABLE HYDROGELS WITH GOLD NANOPARTICLES FOR MEDICAL APPLICATIONS BOSTON SCIENTIFIC SCIMED, INC. (US) 2026-05-28 US disclosed
JP-S59112945-A PREPARATION OF O-SUBSTITUTED-HYDROXYLAMINE KOEI CHEM CO LTD 1984-06-29 JP disclosed
US-4399210-A O-NAPHTHOQUINONEDIAZIDE AND A DISCOLORING AGENT FUJI PHOTO FILM COMPANY LTD. (JP) 1983-08-16 US disclosed
JP-S5551045-A PREPARATION OF ENDORPHIN TAKEDA CHEM IND LTD 1980-04-14 JP disclosed
US-4052373-A O-AMINOESTER FUJI PHOTO FILM CO., LTD. (JA) 1977-10-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10308672-B2 Method for producing monomer for single-stranded nucleic acid molecule DNA2, POLM, POLRMT ALDH1A1 1071/4885POLB 10/4885CASP6 495/4885
US-20070093663-A1 Process for the synthesis of perindopril and pharmaceutically acceptable salts thereof. QDPR, REN, ACE ALDH1A1 82/4885POLB 2909/4885CASP6 1934/4885
US-20190100540-A1 METHOD FOR PRODUCING MONOMER FOR SINGLE-STRANDED NUCLEIC ACID MOLECULE DNA2, POLM, POLRMT ALDH1A1 1071/4885POLB 10/4885CASP6 495/4885
US-20260144900-A1 IN VIVO CROSSLINKABLE HYDROGELS WITH GOLD NANOPARTICLES FOR MEDICAL APPLICATIONS KLK3, BPHL, BRDT ALDH1A1 146/4885POLB 4155/4885CASP6 1123/4885
US-20070123581-A1 Process for the synthesis of (2s, 3as, 7as)-1-[(s)-alanyl]-octahydro-1h-indole-2-carboxylic acid compounds and application in the synthesis of perindopril CYP2S1, TPH1, AGTR1 ALDH1A1 55/4885POLB 3241/4885CASP6 2455/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.