Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 6/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 2/20 | 0.41 |
| ▸ | CCR6 | P51684 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23136163 | 0.90 | KIF11 (0.43) | CACNA1BCYP2D6CNR1CNR2KIF11 | |
| SCHEMBL28662244 | 0.84 | CCR6 (0.40) | CACNA1BCYP2D6CNR1CNR2KIF11 | |
| SCHEMBL15995281 | 0.83 | ALDH1A1 (0.41) | CNR1CNR2MAPT | |
| SCHEMBL5646550 | 0.82 | CNR2 (0.60) | CNR1CNR2KIF11ACHE | |
| SCHEMBL29058872 | 0.78 | KIF11 (0.51) | KIF11ACHEL3MBTL1MAPTNPSR1 | |
| SCHEMBL2005286 | 0.78 | KIF11 (0.44) | KIF11CCR6KCNH2ACHEL3MBTL1 | |
| SCHEMBL20313082 | 0.76 | CNR2 (0.54) | CNR1CNR2KIF11MAPTFAAH | |
| SCHEMBL14025162 | 0.76 | CNR2 (0.68) | CNR1CNR2 | |
| SCHEMBL12409056 | 0.75 | ALDH1A1 (0.42) | KIF11 | |
| SCHEMBL29782607 | 0.75 | L3MBTL1 (0.58) | CYP2D6ACHEL3MBTL1MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7119232-B2 | Nucleophilic substitution reactions of difluorormethyl phenyl sulfone with alkyl halides leading to the facile synthesis of terminal 1,1-difluoro-1-alkenes and difluoromethylalkanes | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2006-10-10 | — | — | US | disclosed |
| US-20060052643-A1 | Nucleophilic substitution reactions of difluorormethyl phenyl sulfone with alkyl halides leading to the facile synthesis of terminal 1,1-difluoro-1-alkenes and difluoromethylalkanes | UNIVERSITY OF SOUTHERN CALIFORNIA | 2006-03-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060052643-A1 | Nucleophilic substitution reactions of difluorormethyl phenyl sulfone with alkyl halides leading to the facile synthesis of terminal 1,1-difluoro-1-alkenes and difluoromethylalkanes | PFAS, FRK, PFKFB1 | CACNA1B 1403/4885CYP2D6 491/4885CNR1 2172/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.