Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAA50 | Q9GZZ1 | 2/20 | 0.87 |
| ▸ | CHAT | P28329 | 2/20 | 0.83 |
| ▸ | EP300 | Q09472 | 3/20 | 0.82 |
| ▸ | KAT5 | Q92993 | 2/20 | 0.82 |
| ▸ | AURKA | O14965 | 2/20 | 0.82 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.82 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19857088 | 0.99 | NAA50 (0.88) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL59721 | 0.99 | NAA50 (0.88) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL22556110 | 0.97 | NAA50 (0.87) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL29530678 | 0.97 | NAA50 (0.87) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL59962 | 0.97 | NAA50 (0.87) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL16585519 | 0.96 | NAA50 (0.84) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL15299842 | 0.96 | NAA50 (0.86) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL19693052 | 0.96 | NAA50 (0.86) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL18918373 | 0.96 | NAA50 (0.85) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL18918369 | 0.96 | NAA50 (0.85) | NAA50CHATEP300KAT5AURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2989113-B1 | MICROORGANISMS AND METHODS FOR PRODUCTION OF 4-HYDROXYBUTYRATE, 1,4-BUTANEDIOL AND RELATED COMPOUNDS | GENOMATICA INC (US) | 2024-04-10 | — | — | EP | disclosed |
| US-11932845-B2 | Microorganisms and methods for production of 4-hydroxybutyrate, 1,4-butanediol and related compounds | GENOMATICA, INC. (US) | 2024-03-19 | — | — | US | disclosed |
| US-20230065295-A1 | MICROORGANISMS AND METHODS FOR PRODUCTION OF 4-HYDROXYBUTYRATE, 1,4-BUTANEDIOL AND RELATED COMPOUNDS | GENOMATICA INC (US) | 2023-03-02 | — | — | US | disclosed |
| US-11572564-B2 | Microorganisms for producing 1,4-butanediol and methods related thereto | GENOMATICA, INC. (US) | 2023-02-07 | — | — | US | disclosed |
| EP-4056706-A1 | MICROORGANISMS FOR THE PRODUCTION OF 1,4-BUTANEDIOL AND RELATED METHODS | Genomatica, Inc. (US) | 2022-09-14 | — | — | EP | disclosed |
| US-11401534-B2 | Microorganisms for the production of 1,4- butanediol and related methods | GENOMATICA, INC. (US) | 2022-08-02 | — | — | US | disclosed |
| EP-3392340-B1 | MICROORGANISMS FOR THE PRODUCTION OF 1,4-BUTANEDIOL AND RELATED METHODS | GENOMATICA INC (US) | 2022-01-05 | — | — | EP | disclosed |
| US-11085015-B2 | Microorganisms and methods for production of 4-hydroxybutyrate, 1,4-butanediol and related compounds | GENOMATICA, INC. (US) | 2021-08-10 | — | — | US | disclosed |
| EP-3831951-A2 | MICROORGANISMS AND METHODS FOR PRODUCTION OF 4-HYDROXYBUTYRATE, 1,4-BUTANEDIOL AND RELATED COMPOUNDS | Genomatica, Inc. (US) | 2021-06-09 | — | — | EP | disclosed |
| EP-2855687-B1 | MICROORGANISMS AND METHODS FOR PRODUCTION OF 4-HYDROXYBUTYRATE, 1,4-BUTANEDIOL AND RELATED COMPOUNDS | GENOMATICA INC (US) | 2020-04-22 | — | — | EP | disclosed |
| US-20110229946-A1 | MICROORGANISMS FOR THE PRODUCTION OF 1,4-BUTANEDIOL, 4-HYDROXYBUTANAL, 4-HYDROXYBUTYRYL-COA, PUTRESCINE AND RELATED COMPOUNDS, AND METHODS RELATED THERETO | GENOMATICA, INC. (US) | 2011-09-22 | — | — | US | disclosed |
| US-20110159572-A1 | MICROORGANISMS FOR THE PRODUCTION OF 1,4-BUTANEDIOL | GENOMATICA, INC. (US) | 2011-06-30 | — | — | US | disclosed |
| EP-2334800-A2 | MICROORGANISMS FOR THE PRODUCTION OF 1,4-BUTANEDIOL | Genomatica, Inc. (US) | 2011-06-22 | — | — | EP | disclosed |
| US-20110129899-A1 | MICROORGANISMS FOR THE PRODUCTION OF 1,4-BUTANEDIOL, 4-HYDROXYBUTANAL, 4-HYDROXYBUTYRYL-COA, PUTRESCINE AND RELATED COMPOUNDS, AND METHODS RELATED THERETO | AGAIN BIO APS (DK) | 2011-06-02 | — | — | US | disclosed |
| WO-2011047101-A1 | MICROORGANISMS FOR THE PRODUCTION OF 1,4-BUTANEDIOL, 4-HYDROXYBUTANAL, 4-HYDROXYBUTYRYL-COA, PUTRESCINE AND RELATED COMPOUNDS, AND METHODS RELATED THERETO | GENOMATICA, INC. (US) | 2011-04-21 | — | — | WO | disclosed |
| US-20110045575-A1 | MICROORGANISMS FOR THE PRODUCTION OF 1,4-BUTANEDIOL AND RELATED METHODS | GENOMATICA, INC. | 2011-02-24 | — | — | US | disclosed |
| US-7858350-B2 | Microorganisms for the production of 1,4-butanediol | GENOMATICA, INC. (US) | 2010-12-28 | — | — | US | disclosed |
| WO-2010141920-A2 | MICROORGANISMS FOR THE PRODUCTION OF 1,4-BUTANEDIOL AND RELATED METHODS | GENOMATICA, INC. (US) | 2010-12-09 | — | — | WO | disclosed |
| US-20100112654-A1 | MICROORGANISMS FOR THE PRODUCTION OF 1,4-BUTANEDIOL | AGAIN BIO APS (DK) | 2010-05-06 | — | — | US | disclosed |
| WO-2010030711-A2 | MICROORGANISMS FOR THE PRODUCTION OF 1,4-BUTANEDIOL | GENOMATICA, INC. (US) | 2010-03-18 | — | — | WO | disclosed |