Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAA50 | Q9GZZ1 | 2/20 | 0.87 |
| ▸ | CHAT | P28329 | 2/20 | 0.83 |
| ▸ | EP300 | Q09472 | 3/20 | 0.82 |
| ▸ | KAT5 | Q92993 | 2/20 | 0.82 |
| ▸ | AURKA | O14965 | 2/20 | 0.82 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.82 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22556110 | 1.00 | NAA50 (0.87) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL59962 | 1.00 | NAA50 (0.87) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL15299842 | 0.98 | NAA50 (0.86) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL19693052 | 0.98 | NAA50 (0.86) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL29396999 | 0.98 | NAA50 (0.85) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL284786 | 0.98 | NAA50 (0.85) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL28041178 | 0.98 | NAA50 (0.85) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL18918369 | 0.98 | NAA50 (0.85) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL28216089 | 0.98 | NAA50 (0.85) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL59721 | 0.97 | NAA50 (0.88) | NAA50CHATEP300KAT5AURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4396334-A2 | FORMATE DEHYDROGENASE VARIANTS AND METHODS OF USE | Genomatica, Inc. (US) | 2024-07-10 | — | — | EP | claimed |
| EP-4305173-A1 | RECOMBINANT MICROORGANISMS AND USES THEREFOR | Lanzatech, Inc. (US) | 2024-01-17 | — | — | EP | claimed |
| WO-2023034745-A2 | FORMATE DEHYDROGENASE VARIANTS AND METHODS OF USE | GENOMATICA, INC. (US) | 2023-03-09 | — | — | WO | claimed |
| WO-2022192865-A9 | RECOMBINANT MICROORGANISMS AND USES THEREFOR | LANZATECH, INC. (US) | 2023-02-09 | — | — | WO | claimed |
| WO-2022217064-A2 | PHOSPHOKETOLASE VARIANTS AND METHODS OF USE | GENOMATICA, INC. (US) | 2022-10-13 | — | — | WO | claimed |
| WO-2022192865-A1 | RECOMBINANT MICROORGANISMS AND USES THEREFOR | LANZATECH, INC. (US) | 2022-09-15 | — | — | WO | claimed |
| CN-116555138-B | ACS mutant of acetyl-CoA synthetase and application thereof in production of 2-pyrrolidone | 森瑞斯生物科技(深圳)有限公司 | 2024-02-13 | — | — | CN | disclosed |
| CN-116555138-A | ACS mutant of acetyl-CoA synthetase and application thereof in production of 2-pyrrolidone | 潍坊亚森生物科技有限公司 | 2023-08-08 | — | — | CN | disclosed |
| EP-4051657-A1 | MICROORGANISMS AND METHODS FOR REDUCING BY-PRODUCTS | Genomatica, Inc. (US) | 2022-09-07 | — | — | EP | disclosed |
| EP-4048781-A1 | MICROORGANISMS AND METHODS FOR INCREASING CO-FACTORS | Genomatica, Inc. (US) | 2022-08-31 | — | — | EP | disclosed |
| WO-2022125645-A1 | OLIVETOLIC ACID CYCLASE VARIANTS AND METHODS FOR THEIR USE | GENOMATICA, INC. (US) | 2022-06-16 | — | — | WO | disclosed |
| EP-3980520-A1 | OLIVETOLIC ACID CYCLASE VARIANTS AND METHODS FOR THEIR USE | Genomatica, Inc. (US) | 2022-04-13 | — | — | EP | disclosed |