Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAA50 | Q9GZZ1 | 2/20 | 0.86 |
| ▸ | CHAT | P28329 | 2/20 | 0.82 |
| ▸ | EP300 | Q09472 | 3/20 | 0.81 |
| ▸ | KAT5 | Q92993 | 2/20 | 0.81 |
| ▸ | AURKA | O14965 | 2/20 | 0.81 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.81 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15299842 | 1.00 | NAA50 (0.86) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL28216089 | 0.99 | NAA50 (0.85) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL29396999 | 0.99 | NAA50 (0.85) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL18918369 | 0.99 | NAA50 (0.85) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL284786 | 0.99 | NAA50 (0.85) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL28041178 | 0.99 | NAA50 (0.85) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL59962 | 0.98 | NAA50 (0.87) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL22556110 | 0.98 | NAA50 (0.87) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL29530678 | 0.98 | NAA50 (0.87) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL59721 | 0.97 | NAA50 (0.88) | NAA50CHATEP300KAT5AURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11046981-B2 | Host cell modified to produce lactams | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-06-29 | — | — | US | disclosed |
| US-20190338321-A1 | Host Cell Modified to Produce Lactams | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-11-07 | — | — | US | disclosed |
| WO-2017214159-A1 | A HOST CELL MODIFIED TO PRODUCE LACTAMS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-12-14 | — | — | WO | disclosed |